Akademska digitalna zbirka SLovenije - logo

Search results

Basic search    Expert search   

Currently you are NOT authorised to access e-resources SI consortium. For full access, REGISTER.

1 2 3 4 5
hits: 57
1.
  • The current landscape of nu... The current landscape of nucleic acid therapeutics
    Kulkarni, Jayesh A; Witzigmann, Dominik; Thomson, Sarah B ... Nature nanotechnology, 06/2021, Volume: 16, Issue: 6
    Journal Article
    Peer reviewed
    Open access

    The increasing number of approved nucleic acid therapeutics demonstrates the potential to treat diseases by targeting their genetic blueprints in vivo. Conventional treatments generally induce ...
Full text
Available for: GEOZS, IJS, IMTLJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBMB, UL, UM, UPUK, ZAGLJ

PDF
2.
  • Nanotechnology for organ-tu... Nanotechnology for organ-tunable gene editing
    van der Meel, Roy Nature nanotechnology, 04/2020, Volume: 15, Issue: 4
    Journal Article
    Peer reviewed
    Open access

    Lipid nanoparticles containing genetic drugs can be bioengineered to tune their biodistribution and induce organ-specific gene regulation.
Full text
Available for: GEOZS, IJS, IMTLJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBMB, UL, UM, UPUK, ZAGLJ

PDF
3.
  • Ligand-targeted particulate... Ligand-targeted particulate nanomedicines undergoing clinical evaluation: Current status
    van der Meel, Roy; Vehmeijer, Laurens J.C.; Kok, Robbert J. ... Advanced drug delivery reviews 65, Issue: 10
    Journal Article
    Peer reviewed
    Open access

    Since the introduction of Doxil® on the market nearly 20years ago, a number of nanomedicines have become part of treatment regimens in the clinic. With the exception of antibody–drug conjugates, ...
Full text
Available for: GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
4.
  • Dexamethasone nanomedicines... Dexamethasone nanomedicines for COVID-19
    Lammers, Twan; Sofias, Alexandros Marios; van der Meel, Roy ... Nature nanotechnology, 08/2020, Volume: 15, Issue: 8
    Journal Article
    Peer reviewed
    Open access

    Nano-formulating dexamethasone, and administering it via intravenous injection or inhalation, may help to improve anti-COVID-19 treatment efficacy by targeting the potent corticosteroid drug to ...
Full text
Available for: GEOZS, IJS, IMTLJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBMB, UL, UM, UPUK, ZAGLJ

PDF
5.
  • Extracellular vesicles as d... Extracellular vesicles as drug delivery systems: Lessons from the liposome field
    van der Meel, Roy; Fens, Marcel H.A.M.; Vader, Pieter ... Journal of controlled release, 12/2014, Volume: 195
    Journal Article
    Peer reviewed

    Extracellular vesicles (EVs) are membrane-derived particles surrounded by a (phospho)lipid bilayer that are released by cells in the human body. In addition to direct cell-to-cell contact and the ...
Full text
Available for: GEOZS, IJS, IMTLJ, KILJ, KISLJ, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UL, UM, UPCLJ, UPUK
6.
  • State‐of‐the‐Art Design and... State‐of‐the‐Art Design and Rapid‐Mixing Production Techniques of Lipid Nanoparticles for Nucleic Acid Delivery
    Evers, Martijn J. W.; Kulkarni, Jayesh A.; der Meel, Roy ... Small methods, September 11, 2018, Volume: 2, Issue: 9
    Journal Article
    Peer reviewed
    Open access

    Lipid nanoparticles (LNPs) are currently the most clinically advanced nonviral carriers for the delivery of small interfering RNA (siRNA). Free siRNA molecules suffer from unfavorable physicochemical ...
Full text
Available for: BFBNIB, FZAB, GIS, IJS, KILJ, NLZOH, NUK, OILJ, SAZU, SBCE, SBMB, UL, UM, UPUK

PDF
7.
Full text

PDF
8.
  • The EPR effect and beyond: ... The EPR effect and beyond: Strategies to improve tumor targeting and cancer nanomedicine treatment efficacy
    Shi, Yang; van der Meel, Roy; Chen, Xiaoyuan ... Theranostics, 01/2020, Volume: 10, Issue: 17
    Journal Article
    Peer reviewed
    Open access

    Following its discovery more than 30 years ago, the enhanced permeability and retention (EPR) effect has become the guiding principle for cancer nanomedicine development. Over the years, the ...
Full text
Available for: NUK, UL, UM, UPUK

PDF
9.
  • Nanomedicine approaches for in vivo cancer immunotherapy
    Hofstraat, Stijn Rj; Anbergen, Tom; der Meel, Roy van Nanomedicine (London, England), 10/2023, Volume: 18, Issue: 23
    Journal Article
    Peer reviewed
    Open access

    Tweetable abstract Commentary just out in @fsgnnm: unleashing the full potential of #cancer #nanomedicines by reprogramming the immunosuppressive #TME using #LNP #mRNA #vaccines and via promoting ...
Full text
10.
  • Lipid Nanoparticle Technolo... Lipid Nanoparticle Technology for Clinical Translation of siRNA Therapeutics
    Kulkarni, Jayesh A; Witzigmann, Dominik; Chen, Sam ... Accounts of chemical research, 09/2019, Volume: 52, Issue: 9
    Journal Article
    Peer reviewed
    Open access

    Conspectus Delivering nucleic acid-based therapeutics to cells is an attractive approach to target the genetic cause of various diseases. In contrast to conventional small molecule drugs that target ...
Full text
Available for: IJS, KILJ, NUK, PNG, UL, UM

PDF
1 2 3 4 5
hits: 57

Load filters