Alkaline water electrolysis is a key technology for large-scale hydrogen production powered by renewable energy. As conventional electrolyzers are designed for operation at fixed process conditions, ...the implementation of fluctuating and highly intermittent renewable energy is challenging. This contribution shows the recent state of system descriptions for alkaline water electrolysis and renewable energies, such as solar and wind power. Each component of a hydrogen energy system needs to be optimized to increase the operation time and system efficiency. Only in this way can hydrogen produced by electrolysis processes be competitive with the conventional path based on fossil energy sources. Conventional alkaline water electrolyzers show a limited part-load range due to an increased gas impurity at low power availability. As explosive mixtures of hydrogen and oxygen must be prevented, a safety shutdown is performed when reaching specific gas contamination. Furthermore, the cell voltage should be optimized to maintain a high efficiency. While photovoltaic panels can be directly coupled to alkaline water electrolyzers, wind turbines require suitable converters with additional losses. By combining alkaline water electrolysis with hydrogen storage tanks and fuel cells, power grid stabilization can be performed. As a consequence, the conventional spinning reserve can be reduced, which additionally lowers the carbon dioxide emissions.
Being the earliest form of additive manufacturing, stereolithography (SLA) fabricates 3D objects by selectively solidifying the liquid resin through a photopolymerization reaction. The ability to ...fabricate objects with high accuracy as well as a wide variety of materials brings much attention to stereolithography. Since its invention in the 1980s, SLA underwent four generations of major technological innovation over the past 40 years. These innovations have thus resulted in a diversified range of stereolithography systems with dramatically improved resolution, throughput, and materials selection for creating complex 3D objects and devices. In this paper, we review the four generations of stereolithography processes, which are scanning, projection, continuous and volumetric stereolithography. For each generation, representative stereolithography system configurations are also discussed in detail. In addition, other derivative technologies, such as scanning–projection, multi-material, and magnetically assisted stereolithography processes, are also included in this review.
The flow and heat transfer of non-Newtonian nanofluids has an extensive range of applications in oceanography, the cooling of metallic plates, melt-spinning, the movement of biological fluids, heat ...exchangers technology, coating and suspensions. In view of these applications, we studied the steady Marangoni driven boundary layer flow, heat and mass transfer characteristics of a nanofluid. A non-Newtonian second-grade liquid model is used to deliberate the effect of activation energy on the chemically reactive non-Newtonian nanofluid. By applying suitable similarity transformations, the system of governing equations is transformed into a set of ordinary differential equations. These reduced equations are tackled numerically using the Runge–Kutta–Fehlberg fourth-fifth order (RKF-45) method. The velocity, concentration, thermal fields and rate of heat transfer are explored for the embedded non-dimensional parameters graphically. Our results revealed that the escalating values of the Marangoni number improve the velocity gradient and reduce the heat transfer. As the values of the porosity parameter increase, the velocity gradient is reduced and the heat transfer is improved. Finally, the Nusselt number is found to decline as the porosity parameter increases.
Molecular dynamics (MD) simulations have become increasingly useful in the modern drug development process. In this review, we give a broad overview of the current application possibilities of MD in ...drug discovery and pharmaceutical development. Starting from the target validation step of the drug development process, we give several examples of how MD studies can give important insights into the dynamics and function of identified drug targets such as sirtuins, RAS proteins, or intrinsically disordered proteins. The role of MD in antibody design is also reviewed. In the lead discovery and lead optimization phases, MD facilitates the evaluation of the binding energetics and kinetics of the ligand-receptor interactions, therefore guiding the choice of the best candidate molecules for further development. The importance of considering the biological lipid bilayer environment in the MD simulations of membrane proteins is also discussed, using G-protein coupled receptors and ion channels as well as the drug-metabolizing cytochrome P450 enzymes as relevant examples. Lastly, we discuss the emerging role of MD simulations in facilitating the pharmaceutical formulation development of drugs and candidate drugs. Specifically, we look at how MD can be used in studying the crystalline and amorphous solids, the stability of amorphous drug or drug-polymer formulations, and drug solubility. Moreover, since nanoparticle drug formulations are of great interest in the field of drug delivery research, different applications of nano-particle simulations are also briefly summarized using multiple recent studies as examples. In the future, the role of MD simulations in facilitating the drug development process is likely to grow substantially with the increasing computer power and advancements in the development of force fields and enhanced MD methodologies.
Phosphates in wastewater at elevated concentrations cause eutrophication of water bodies and their removal from treated wastewater is essential before effluents are discharged to the environment. ...Phosphates are predominately removed during wastewater treatment by chemical precipitation which is usually expensive and has a significant environmental footprint. The purpose of this study was to investigate the effectiveness of waste recycled bricks as adsorbent for phosphate removal during wastewater treatment. The kinetics, isotherms, and thermodynamics of adsorption were investigated to establish the mechanisms of adsorption. The results showed that adsorption capacities increased with an increase in contact time, adsorbent dosage, and initial phosphate concentration. The kinetic study indicated that adsorption was governed by several mechanisms with various processes dominating different stages of the adsorption. The adsorption process was better represented by the pseudo-second-order kinetics and the Langmuir isotherm adequately described the adsorption of phosphates onto brick particles with a maximum adsorption capacity of 5.35 mg/g. The thermodynamic studies showed that the adsorption process was exothermic and proceeded spontaneously, demonstrating that waste bricks can be used as a sustainable alternative for the effective removal of phosphates from wastewater.
Wind energy is contributing to more and more portions in the world energy market. However, one deterrent to even greater investment in wind energy is the considerable failure rate of turbines. In ...particular, large wind turbines are expensive, with less tolerance for system performance degradations, unscheduled system shut downs, and even system damages caused by various malfunctions or faults occurring in system components such as rotor blades, hydraulic systems, generator, electronic control units, electric systems, sensors, and so forth. As a result, there is a high demand to improve the operation reliability, availability, and productivity of wind turbine systems. It is thus paramount to detect and identify any kinds of abnormalities as early as possible, predict potential faults and the remaining useful life of the components, and implement resilient control and management for minimizing performance degradation and economic cost, and avoiding dangerous situations. During the last 20 years, interesting and intensive research results were reported on fault diagnosis, prognosis, and resilient control techniques for wind turbine systems. This paper aims to provide a state-of-the-art overview on the existing fault diagnosis, prognosis, and resilient control methods and techniques for wind turbine systems, with particular attention on the results reported during the last decade. Finally, an overlook on the future development of the fault diagnosis, prognosis, and resilient control techniques for wind turbine systems is presented.
Natural extracts have been widely used to protect metal materials from corrosion. The efficiency of these extracts as corrosion inhibitors is commonly evaluated through electrochemical tests, which ...include techniques such as potentiodynamic polarization, electrochemical impedance spectroscopy, and weight loss measurement. The inhibition efficiency of different extract concentrations is a valuable indicator to obtain a clear outlook to choose an extract for a particular purpose. A complementary vision of the effectiveness of green extracts to inhibit the corrosion of metals is obtained by means of surface characterizations; atomic force microscopy, scanning electron microscopy, and X-ray photoelectron spectroscopy analysis are experimental techniques widely used for this purpose. Moreover, theoretical studies are usually addressed to elucidate the nature of the corrosion inhibitor—metal surface interactions. In addition, calculations have been employed to predict how other organic substances behave on metal surfaces and to provide experimental work with fresh proposals. This work reports a broad overview of the current state of the art research on the study of new extracts as corrosion inhibitors on metal surfaces in corrosive media. Most constituents obtained from plant extracts are adsorbed on the metal, following the Langmuir adsorption model. Electron-rich regions and heteroatoms have been found to be responsible for chemisorption on the metal surface, whereas physisorption is due to the polar regions of the inhibitor molecules. The plant extracts compiled in this work obtained corrosion inhibition efficiencies above 60%, most of them around 80–90%. The effect of concentration, extraction solvent, temperature, and immersion time were studied as well. Additional studies regarding plant extracts as corrosion inhibitors on metals are needed to produce solutions for industrial purposes.
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