Human papillomavirus and cervical cancer Crosbie, Emma J, PhD; Einstein, Mark H, MD; Franceschi, Silvia, MD ...
The Lancet (British edition),
09/2013, Volume:
382, Issue:
9895
Journal Article
Peer reviewed
Summary Cervical cancer is caused by human papillomavirus infection. Most human papillomavirus infection is harmless and clears spontaneously but persistent infection with high-risk human ...papillomavirus (especially type 16) can cause cancer of the cervix, vulva, vagina, anus, penis, and oropharynx. The virus exclusively infects epithelium and produces new viral particles only in fully mature epithelial cells. Human papillomavirus disrupts normal cell-cycle control, promoting uncontrolled cell division and the accumulation of genetic damage. Two effective prophylactic vaccines composed of human papillomavirus type 16 and 18, and human papillomavirus type 16, 18, 6, and 11 virus-like particles have been introduced in many developed countries as a primary prevention strategy. Human papillomavirus testing is clinically valuable for secondary prevention in triaging low-grade cytology and as a test of cure after treatment. More sensitive than cytology, primary screening by human papillomavirus testing could enable screening intervals to be extended. If these prevention strategies can be implemented in developing countries, many thousands of lives could be saved.
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12.
Animism in rainforest and tundra Brightman, Marc; Grotti, Vanessa Elisa; Ulturgasheva, Olga
2012, 2014., 20120815, 2012-08-15, 20120101
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Amazonia and Siberia, classic regions of shamanism, have long challenged 'western' understandings of man's place in the world. By exploring the social relations between humans and non-human entities ...credited with human-like personhood (not only animals and plants, but also 'things' such as artifacts, trade items, or mineral resources) from a comparative perspective, this volume offers valuable insights into the constitutions of humanity and personhood characteristic of the two areas. The contributors conducted their ethnographic fieldwork among peoples undergoing transformative processes of their lived environments, such as the depletion of natural resources and migration to urban centers. They describe here fundamental relational modes that are being tested in the face of change, presenting groundbreaking research on personhood and agency in shamanic societies and contributing to our global understanding of social and cultural change and continuity.
In one of the first ever environmental histories of the Ottoman Empire, Alan Mikhail examines relations between the empire and its most lucrative province of Egypt. Based on both the local records of ...various towns and villages in rural Egypt and the imperial orders of the Ottoman state, this book charts how changes in the control of natural resources fundamentally altered the nature of Ottoman imperial sovereignty in Egypt and throughout the empire. In revealing how Egyptian peasants were able to use their knowledge and experience of local environments to force the hand of the imperial state, Nature and Empire in Ottoman Egypt tells a story of the connections of empire stretching from canals in the Egyptian countryside to the palace in Istanbul, from the forests of Anatolia to the shores of the Red Sea, and from a plague flea's bite to the fortunes of one of the most powerful states of the early modern world.
From the tombs of the elite to the graves of commoners, mortuary remains offer rich insights into Classic Maya society. In Mortuary Landscapes of the Classic Maya: Rituals of Body and Soul, the ...anthropological archaeologist and bioarchaeologist Andrew K. Scherer explores the broad range of burial practices among the Maya of the Classic period (AD 250–900), integrating information gleaned from his own fieldwork with insights from the fields of iconography, epigraphy, and ethnography to illuminate this society’s rich funerary traditions.Scherer’s study of burials along the Usumacinta River at the Mexican-Guatemalan border and in the Central Petén region of Guatemala—areas that include Piedras Negras, El Kinel, Tecolote, El Zotz, and Yaxha—reveals commonalities and differences among royal, elite, and commoner mortuary practices. By analyzing skeletons containing dental and cranial modifications, as well as the adornments of interred bodies, Scherer probes Classic Maya conceptions of body, wellness, and the afterlife. Scherer also moves beyond the body to look at the spatial orientation of the burials and their integration into the architecture of Maya communities. Taking a unique interdisciplinary approach, the author examines how Classic Maya deathways can expand our understanding of this society’s beliefs and traditions, making Mortuary Landscapes of the Classic Maya an important step forward in Mesoamerican archeology.
We summarize several methods we have used to create software and processes for automated methods for content creation for augmented reality, virtual reality, and other 3D medium uses and beyond. We ...utilize processes involving, machine learning semantic segmentation, computer vision geometry recognition for automated texture mapping, photogrammetry 3D reconstruction from 2D images and videogrammetry video content, and more. A practical use in industry is an emphasis for each software example, and many are associated with awards.
This book examines the existing evidence to support these practices as well as the risks associated with various types of programs. This robust volume features detailed discussion of topics that ...include human-animal interactions in specific patient populations and settings, as well as best practices for ensuring animal welfare and well-being.
In Hidden Depths, Professor Penny Spikins explores how our emotional connections have shaped human ancestry. Focusing on three key transitions in human origins, Professor Spikins explains how the ...emotional capacities of our early ancestors evolved in response to ecological changes, much like similar changes in other social mammals. For each transition, dedicated chapters examine evolutionary pressures, responses in changes in human emotional capacities and the archaeological evidence for human social behaviours. Starting from our earliest origins, in Part One, Professor Spikins explores how after two million years ago, movement of human ancestors into a new ecological niche drove new types of collaboration, including care for vulnerable members of the group. Emotional adaptations lead to cognitive changes, as new connections based on compassion, generosity, trust and inclusion also changed our relationship to material things. Part Two explores a later key transition in human emotional capacities occurring after 300,000 years ago. At this time changes in social tolerance allowed ancestors of our own species to further reach out beyond their local group and care about distant allies, making human communities resilient to environmental changes. An increasingly close relationship to animals, and even to cherished possessions, appeared at this time, and can be explained through new human vulnerabilities and ways of seeking comfort and belonging. Lastly, Part Three focuses on the contrasts in emotional dispositions arising between ourselves and our close cousins, the Neanderthals. Neanderthals are revealed as equally caring yet emotionally different humans, who might, if things had been different, have been in our place today. This new narrative breaks away from traditional views of human evolution as exceptional or as a linear progression towards a more perfect form. Instead, our evolutionary history is situated within similar processes occurring in other mammals, and explained as one in which emotions, rather than ‘intellect’, were key to our evolutionary journey. Moreover, changes in emotional capacities and dispositions are seen as part of differing pathways each bringing strengths, weaknesses and compromises. These hidden depths provide an explanation for many of the emotional sensitivities and vulnerabilities which continue to influence our world today.
How do we understand the agency and significance of material forces and their interface with human bodies? What does it mean to be human in these times, with bodies that are inextricably ...interconnected with our physical world? Bodily Natures considers these questions by grappling with powerful and pervasive material forces and their increasingly harmful effects on the human body. Drawing on feminist theory, environmental studies, and the sciences, Stacy Alaimo focuses on trans-corporeality, or movement across bodies and nature, which has profoundly altered our sense of self. By looking at a broad range of creative and philosophical writings, Alaimo illuminates how science, politics, and culture collide, while considering the closeness of the human body to the environment.
What happens if we abandon the assumption that a person is a discrete, world-making agent who acts on and creates place? This, Monique Allewaert contends, is precisely what occurred on ...eighteenth-century American plantations, where labor practices and ecological particularities threatened the literal and conceptual boundaries that separated persons from the natural world. Integrating political philosophy and ecocriticism with literary analysis, Ariel's Ecology explores the forms of personhood that developed out of New World plantations, from Georgia and Florida through Jamaica to Haiti and extending into colonial metropoles such as Philadelphia. Allewaert's examination of the writings of naturalists, novelists, and poets; the oral stories of Africans in the diaspora; and Afro-American fetish artifacts shows that persons in American plantation spaces were pulled into a web of environmental stresses, ranging from humidity to the demand for sugar. This in turn gave rise to modes of personhood explicitly attuned to human beings' interrelation with nonhuman forces in a process we might call ecological. Certainly the possibility that colonial life revokes human agency haunts works from Shakespeare's Tempest and Montesquieu's Spirit of the Laws to Spivak's theories of subalternity. In Allewaert's interpretation, the transformation of colonial subjectivity into ecological personhood is not a nightmare; it is, rather, a mode of existence until now only glimmering in Che Guevara's dictum that postcolonial resistance is synonymous with "perfect knowledge of the ground."
With this book Kuntala Lahiri-Dutt and Gopa Samanta offer an intimate glimpse into the microcosmic world of "hybrid landscapes." Focusing on chars-the part-land, part-water, low-lying sandy masses ...that exist within the riverbeds in the floodplains of lower Bengal-the authors show how, both as real-life examples and as metaphors, chars straddle the conventional categories of land and water, and how people who live on them fluctuate between legitimacy and illegitimacy. The result, a study of human habitation in the nebulous space between land and water, charts a new way of thinking about land, people, and people's ways of life.