A Physarum machine is a programmable amorphous biological computer experimentally implemented in the vegetative state of true slime mould Physarum polycephalum. It comprises an amorphous yellowish ...mass with networks of protoplasmic veins, programmed by spatial configurations of attracting and repelling gradients.
With the continuous and stable development of the global economy, ports play a vital role as cargo transhipment hubs. Among them, the human factor of the operators in the port plays a decisive role ...in the port service ability. In order to explore the specific effects of different fatigue states of the quay bridge, yard bridge, and internal truck operators in the traditional container terminal on the port’s service capacity, seven test schemes are proposed, and computer simulation methods are used to build a simulation model of the terminal. Through a large number of simulation tests, it is concluded that the fatigue of different equipment operators has different effects on the operation efficiency of the terminal. If the three operators are fatigued at the same time, the operation efficiency of the terminal will be reduced by 17.27%, which will have a very negative impact on the overall operation of the terminal. Therefore, optimizing the scheduling of operators and avoiding fatigue operations will improve the port’s service capacity.
A couple ring enclosed circular geometric resonator (CRECGR) based dual-band polarization insensitive metamaterial (MM) with high effective medium ratio (EMR), and excellent absorptance is proposed ...in this study, which can be utilized as a sensor and absorber in the 5G sub-6 GHz frequency range. A circular geometry-based unique patch has been introduced in the proposed unit cell to achieve high polarization insensitive properties with excellent absorption for the 5G sub-6 GHz spectrum. The distinctive feature of this proposed CRECGR unit cell is its simple and unique structure with a high EMR of 11.13, polarization insensitive up to 180°, and epsilon negative (ENG) properties, including a negative refractive index and near-zero permeability for 5G sub-6 GHz applications. Furthermore, this designed unit cell yields excellent absorption properties with high quality factor. The designed MM unit cell is fabricated on low loss Rogers RT5880 printed media with an electrical dimension of 0.089λ × 0.089λ × 0.017λ. The performance of the designed CRECGR metamaterial is determined using Computer Simulation Technology (CST), Advanced Design Software (ADS), and measurements. The CRECGR unit cell offers dual resonances at 3.37 GHz and 5.8 GHz, covering the 5G sub-6 GHz band with ENG, near-zero permeability and negative index. The polarization insensitive properties of the unit cell were also investigated for maximum angle of incidence, which confirmed the identical response. The simulated outcome is verified by experiment with excellent accordance. Moreover, the unit cell performance with a complete backplane is explored, noting a maximum absorption of 99.9% for all normal and oblique incidence waves, suitable for sensing and antenna systems. In addition, the suggested unit cell sensing performance is evaluated using the permittivity-based sensing model. The proposed MM outperforms recent related studies in terms of polarization insensitivity up to 180°, high insensitive absorptivity, high EMR, and sensing applications. These features prove that the proposed CRECGR metamaterial is perfect for 5G Applications.
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The molecular details of biomolecular kinetics present a challenging estimation problem because the identities of relevant intermediates and the rates of exchange between them must be determined. ...These can be derived from prior knowledge, but in recent years, great advances have been made in the development and application of methods to systematically determine states and rates using biomolecular simulation. Doing this for biological systems of reasonable complexity requires substantial computational power, and contemporary methods leverage distributed computing or leadership-class computing resources to accomplish this. The result has been substantial insight into pressing contemporary problems, including structural activation of pandemic viruses. Here, we highlight recent developments in both methodology and exciting applications.
•Ensemble simulation provides an efficient way to estimate biomolecular kinetics.•Recent algorithmic advances improve unbiased sampling and model generation from ensemble datasets.•Such approaches have yielded insight into protein-protein binding, the biomolecular dynamics of viral entry, and other areas.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
An introduction to technical details related to the Physical Layer of the LTE standard with MATLAB® The LTE (Long Term Evolution) and LTE-Advanced are among the latest mobile communications ...standards, designed to realize the dream of a truly global, fast, all-IP-based, secure broadband mobile access technology. This book examines the Physical Layer (PHY) of the LTE standards by incorporating three conceptual elements: an overview of the theory behind key enabling technologies; a concise discussion regarding standard specifications; and the MATLAB® algorithms needed to simulate the standard. The use of MATLAB®, a widely used technical computing language, is one of the distinguishing features of this book. Through a series of MATLAB® programs, the author explores each of the enabling technologies, pedagogically synthesizes an LTE PHY system model, and evaluates system performance at each stage. Following this step-by-step process, readers will achieve deeper understanding of LTE concepts and specifications through simulations. Key Features: Accessible, intuitive, and progressive; one of the few books to focus primarily on the modeling, simulation, and implementation of the LTE PHY standard Includes case studies and testbenches in MATLAB®, which build knowledge gradually and incrementally until a functional specification for the LTE PHY is attained Accompanying Web site includes all MATLAB® programs, together with PowerPoint slides and other illustrative examples
The UVA/PADOVA Type 1 Diabetes Simulator Man, Chiara Dalla; Micheletto, Francesco; Lv, Dayu ...
Journal of diabetes science and technology,
01/2014, Volume:
8, Issue:
1
Journal Article
Peer reviewed
Objective:
Recent studies have provided new insights into nonlinearities of insulin action in the hypoglycemic range and into glucagon kinetics as it relates to response to hypoglycemia. Based on ...these data, we developed a new version of the UVA/PADOVA Type 1 Diabetes Simulator, which was submitted to FDA in 2013 (S2013).
Methods:
The model of glucose kinetics in hypoglycemia has been improved, implementing the notion that insulin-dependent utilization increases nonlinearly when glucose decreases below a certain threshold. In addition, glucagon kinetics and secretion and action models have been incorporated into the simulator: glucagon kinetics is a single compartment; glucagon secretion is controlled by plasma insulin, plasma glucose below a certain threshold, and glucose rate of change; and plasma glucagon stimulates with some delay endogenous glucose production. A refined statistical strategy for virtual patient generation has been adopted as well. Finally, new rules for determining insulin to carbs ratio (CR) and correction factor (CF) of the virtual patients have been implemented to better comply with clinical definitions.
Results:
S2013 shows a better performance in describing hypoglycemic events. In addition, the new virtual subjects span well the real type 1 diabetes mellitus population as demonstrated by good agreement between real and simulated distribution of patient-specific parameters, such as CR and CF.
Conclusions:
S2013 provides a more reliable framework for in silico trials, for testing glucose sensors and insulin augmented pump prediction methods, and for closed-loop single/dual hormone controller design, testing, and validation.
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Every workday we wrestle with cumbersome and unintuitive technologies. Our response is usually "That's just the way it is." Even technology designers and workplace managers believe that certain ...technological changes are inevitable and that they will bring specific, unavoidable organizational changes. In this book, Paul Leonardi offers a new conceptual framework for understanding why technologies and organizations change as they do and why people think those changes had to occur as they did. He argues that technologies and the organizations in which they are developed and used are not separate entities; rather, they are made up of the same building blocks: social agency and material agency. Over time, social agency and material agency become imbricated--gradually interlocked--in ways that produce some changes we call "technological" and others we call "organizational." Drawing on a detailed field study of engineers at a U.S. auto company, Leonardi shows that as the engineers developed and used a a new computer-based simulation technology for automotive design, they chose to change how their work was organized, which then brought new changes to the technology.Each imbrication of the social and the material obscured the actors' previous choices, making the resulting technological and organizational structures appear as if they were inevitable. Leonardi suggests that treating organizing as a process of sociomaterial imbrication allows us to recognize and act on the flexibility of information technologies and to create more effective work organizations.
This book covers a wide range of applications and uses of simulation and modeling techniques in polymer injection molding, filling a noticeable gap in the literature of design, manufacturing, and the ...use of plastics injection molding. The authors help readers solve problems in the advanced control, simulation, monitoring, and optimization of injection molding processes. The book provides a tool for researchers and engineers to calculate the mold filling, optimization of processing control, and quality estimation before prototype molding.