Multigene and genomic data sets have become commonplace in the field of phylogenetics, but many existing tools are not designed for such data sets, which often makes the analysis time‐consuming and ...tedious. Here, we present PhyloSuite, a (cross‐platform, open‐source, stand‐alone Python graphical user interface) user‐friendly workflow desktop platform dedicated to streamlining molecular sequence data management and evolutionary phylogenetics studies. It uses a plugin‐based system that integrates several phylogenetic and bioinformatic tools, thereby streamlining the entire procedure, from data acquisition to phylogenetic tree annotation (in combination with iTOL). It has the following features: (a) point‐and‐click and drag‐and‐drop graphical user interface; (b) a workplace to manage and organize molecular sequence data and results of analyses; (c) GenBank entry extraction and comparative statistics; and (d) a phylogenetic workflow with batch processing capability, comprising sequence alignment (mafft and macse), alignment optimization (trimAl, HmmCleaner and Gblocks), data set concatenation, best partitioning scheme and best evolutionary model selection (PartitionFinder and modelfinder), and phylogenetic inference (MrBayes and iq‐tree). PhyloSuite is designed for both beginners and experienced researchers, allowing the former to quick‐start their way into phylogenetic analysis, and the latter to conduct, store and manage their work in a streamlined way, and spend more time investigating scientific questions instead of wasting it on transferring files from one software program to another.
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In the last decade, maybe longer, the oil, gas and chemical (OGC) industry has seen a decline in the electric power engineering ranks and knowledge base. With the advent of the pandemic and the great ...resignation that followed, the industry has seen an acceleration of this knowledge drain. As experienced workers retire, knowledge around engineering and design of electrical systems and the application of various products is leaving with them, and hence engineers are being tasked with doing more sooner. Many universities have shifted the focus of their curriculums to cater to the field of high tech, leaving only a handful of institutions with strong programs in electric power engineering and subfields such as electric machines, power electronics, and power systems. Addressing skill gaps has become a point of discussion from break rooms to board rooms. One clear example is the sizing of Medium and Low Voltage power cables, which are critical to the supply of electric power in all industries. Selecting and sizing cables can have a material impact on the overall reliability, safety, and CAPEX cost of a project. This article discusses a cable sizing flowchart tool as a means to mitigate the knowledge drain caused by engineers retiring and resigning in the OGC industry. The tool brings relevant knowledge that resides in the National Electrical Code (NEC) around cables and selecting the right size of cable using the Low Voltage Cable Sizing Flowchart in Appendix <xref ref-type="app" rid="app1">A , based on 2023 NEC. The goal of the paper is to provide a handy reference cable sizing guide for the early career professional who is asked to make cable selections and to serve as a springboard for further reference depending on the specific application that the engineer might be tasked with.
This research aimed at finding out the use of flowchart in improving the ability of the fifth semester students of Informatics Engineering Study Program of Cokroaminoto Palopo University to write ...paragraph and to find out the interest of the students to write paragraph by using flowchart. This research was pre-experimental. Independent variable of the research is using flowchart in writing a paragraph and dependent variable is the ability of students to write a paragraph. The population of the research was the fifth semester students of Informatics Engineering Study Program of Universitas Cokroaminoto Palopo. The sample was one class of the fifth semester students of Informatics Engineering Study Program of Universitas Cokroaminoto Palopo. The result shows that flowchart is effective to use in improving students’ ability in writing because there was a significant difference between the progresses in writing of the students who were studying through flowchart and those are not. By flowchart strategy, the students can express their ideas easily without stopping and rushing. It gave them writing power and easy to understand.
This narrative review describes up-to-date treatment options for peri-implantitis and proposes a treatment protocol and flowchart based on the current scientific evidence. Peri-implantitis treatment ...should be based on the phased treatment protocol for periodontitis, which is a continuous flow of decisions for extraction, nonsurgical and surgical treatments with step-by-step re-evaluation. The protocol's goals are to fulfill the success criteria for peri-implantitis treatment (probing depth of ≤5 mm, and absence of bleeding on probing, suppuration, and progressive bone loss) and to halt disease progression. Fixtures with peri-implantitis can initially be classified as failed or failing. A failed implant needs to be removed. In contrast, nonsurgical and surgical treatments can be applied to a failing implant. Nonsurgical treatment should be the initial treatment for failing implants; however, sole nonsurgical treatment was regarded as inefficient for peri-implantitis. Recent studies have found that the adjunctive use of antibiotics to nonsurgical debridement increased the success of nonsurgical treatment for peri-implantitis. Surgical treatments can be classified into resective, access, and reconstructive surgeries. The technique should be selected according to the patient's bone defect configuration, which relate to regenerative potential. Various combinations of decontamination methods (e.g., mechanical, chemical, and pharmacological approaches) are required to achieve absolute surface decontamination. Clinicians should select an appropriate surface decontamination strategy according to the purpose of surgery. After signs of disease disappear and its progression is halted through active peri-implantitis treatment, it is necessary to enroll patients into maintenance programs. Compliance of patients with the maintenance program reduces the recurrence of peri-implantitis and sustains clinical success after treatment. Maintenance visits should include professional plaque control and hygiene care reinforcement for patients, and their interval should be set according to individual peri-implantitis risk. Clinicians should remind that peri-implantitis treatment is not a single procedure, but rather a continuing cycle of treatment and re-evaluation.
Penelitian ini bertujuan untuk merancang dan mengembangkan sistem kuis algoritma pemrograman berbasis web dan mengetahui validitas sistem kuis algoritma pemrograman berbasis web. Berdasarkan hasil ...pengamatan pada mahasiswa, ditemukan fakta yang menunjukkan permasalahan pada pemahaman untuk menyelesaikan permasalahan dalam pemrograman komputer. Informasi didapatkan dengan menyebarkan kuesioner pada mahasiswa. Dari informasi tersebut, didapatkan data bahwa algoritma merupakan materi pada pemrograman yang paling penting. Hasil penelitian menunjukkan, penilaian kelayakan sistem kuis algoritma pemrograman oleh ahli media mendapatkan perolehan data sebesar 85,71% pada aspek penggunaan, 85% pada aspek desain, dan 85% pada aspek fungsi. Dengan rata-rata perolehan data sebesar 85,29%. Dari hasil penelitian tersebut maka dapat disimpulkan bahwa sistem kuis algoritma pemrograman yang telah dikembangkan sudah layak digunakan dengan revisi kecil.
Supermicrosurgical lymphaticovenular anastomosis represents an established procedure for lymphedema treatment, the effectiveness of which has been well documented in international ...literature.Nevertheless, currently, no standards for supermicrosurgical lymphaticovenular anastomosis have been established regarding the type, location, and number of anastomoses so that the approach to surgical scenarios still depends on the surgeons' preference and ability.A comprehensive literature search for articles involving supermicrosurgical lymphaticovenular anastomosis techniques was performed on the PubMed/Medline/SCOPUS databases. Results, including the names of the technique and their characteristics, such as indications, surgical time, and configuration of the vessels, are reported.Each technique included was then performed five times, and for each of them, patency was tested intraoperatively and 30 days after surgery. Moreover, an efficacy score was assigned, taking into consideration the number of lymphatic vessels anastomosed, the average time for anastomosis, and the difficulty of each technique.A total of 148 articles resulted from the literature search. In total, 16 papers met the criteria for inclusion as defined in the methods and were included in the review as a "supermicrosurgical lymphaticovenular anastomosis technique." Efficacy scores ranged from 0.21 to 1, intraoperative patency ranged from 80% to 100%, and the 30-days patency test ranged from 60% to 100%.To perform effective anastomoses and aim to maximize the results of supermicrosurgical lymphaticovenular anastomosis, a modern microsurgeon should be trained to recognize and manage the most common vessel configurations, performing the most adequate one of the several techniques described. Further studies are required to validate and compare the use of the supermicrosurgical lymphaticovenular anastomosis techniques reviewed.
Supermicrosurgical lymphaticovenular anastomosis represents an established procedure for lymphedema treatment, the effectiveness of which has been well documented in international literature. ...Nevertheless, currently, no standards for supermicrosurgical lymphaticovenular anastomosis have been established regarding the type, location, and number of anastomoses so that the approach to surgical scenarios still depends on the surgeons' preference and ability. A comprehensive literature search for articles involving supermicrosurgical lymphaticovenular anastomosis techniques was performed on the PubMed/Medline/SCOPUS databases. Results, including the names of the technique and their characteristics, such as indications, surgical time, and configuration of the vessels, are reported. Each technique included was then performed five times, and for each of them, patency was tested intraoperatively and 30 days after surgery. Moreover, an efficacy score was assigned, taking into consideration the number of lymphatic vessels anastomosed, the average time for anastomosis, and the difficulty of each technique. A total of 148 articles resulted from the literature search. In total, 16 papers met the criteria for inclusion as defined in the methods and were included in the review as a “supermicrosurgical lymphaticovenular anastomosis technique.” Efficacy scores ranged from 0.21 to 1, intraoperative patency ranged from 80% to 100%, and the 30-days patency test ranged from 60% to 100%. To perform effective anastomoses and aim to maximize the results of supermicrosurgical lymphaticovenular anastomosis, a modern microsurgeon should be trained to recognize and manage the most common vessel configurations, performing the most adequate one of the several techniques described. Further studies are required to validate and compare the use of the supermicrosurgical lymphaticovenular anastomosis techniques reviewed.
Autonomous control system road construction machine Sukharev, Roman; Semkin, Dmitry; Ignatov, Sergey
Nauchno-tekhnicheskiĭ vestnik Bri͡a︡nskogo gosudarstvennogo universiteta,
03/2024, Volume:
10, Issue:
1
Journal Article
Peer reviewed
Open access
The increasing requirements for the accuracy of construction work lead to the need to create modern control systems that will eliminate the human operator from the process of controlling road ...construction machines, increase the energy efficiency and productivity of these machines, as well as the quality of the finished construction object. The use of unmanned control systems has become an absolute technological break-through. Improving the accuracy of work with the help of unmanned control systems is an urgent and complex area of research. This is due to the need to improve algorithms and improve sensors to more accurately de-termine the coordinates of the machine and make decisions. Only by possessing high accuracy, modern unmanned vehicles are able to minimize errors in construction work and associated safety risks. To do this, it is necessary to provide the ability to recognize and analyze various factors, such as moving objects, weather conditions, terrain, etc. The article presents the results of a functional analysis of a number of road construction machines, defines the range of tasks that a modern unmanned control system should solve, describes a possible implementation option for such a system, and shows the differences in flowcharts of working processes of construction machines both without automatic control systems and equipped with standard and developed automatic control systems.
Supermicrosurgical lymphaticovenular anastomosis represents an established procedure for lymphedema treatment, the effectiveness of which has been well documented in international ...literature.Nevertheless, currently, no standards for supermicrosurgical lymphaticovenular anastomosis have been established regarding the type, location, and number of anastomoses so that the approach to surgical scenarios still depends on the surgeons' preference and ability.A comprehensive literature search for articles involving supermicrosurgical lymphaticovenular anastomosis techniques was performed on the PubMed/Medline/SCOPUS databases. Results, including the names of the technique and their characteristics, such as indications, surgical time, and configuration of the vessels, are reported.Each technique included was then performed five times, and for each of them, patency was tested intraoperatively and 30 days after surgery. Moreover, an efficacy score was assigned, taking into consideration the number of lymphatic vessels anastomosed, the average time for anastomosis, and the difficulty of each technique.A total of 148 articles resulted from the literature search. In total, 16 papers met the criteria for inclusion as defined in the methods and were included in the review as a "supermicrosurgical lymphaticovenular anastomosis technique." Efficacy scores ranged from 0.21 to 1, intraoperative patency ranged from 80% to 100%, and the 30-days patency test ranged from 60% to 100%.To perform effective anastomoses and aim to maximize the results of supermicrosurgical lymphaticovenular anastomosis, a modern microsurgeon should be trained to recognize and manage the most common vessel configurations, performing the most adequate one of the several techniques described. Further studies are required to validate and compare the use of the supermicrosurgical lymphaticovenular anastomosis techniques reviewed.
We propose a new flowchart for the treatment of acute cholecystitis (AC) in the Tokyo Guidelines 2018 (TG18). Grade III AC was not indicated for straightforward laparoscopic cholecystectomy (Lap‐C). ...Following analysis of subsequent clinical investigations and drawing on Big Data in particular, TG18 proposes that some Grade III AC can be treated by Lap‐C when performed at advanced centers with specialized surgeons experienced in this procedure and for patients that satisfy certain strict criteria. For Grade I, TG18 recommends early Lap‐C if the patients meet the criteria of Charlson comorbidity index (CCI) ≤5 and American Society of Anesthesiologists physical status classification (ASA‐PS) ≤2. For Grade II AC, if patients meet the criteria of CCI ≤5 and ASA‐PS ≤2, TG18 recommends early Lap‐C performed by experienced surgeons; and if not, after medical treatment and/or gallbladder drainage, Lap‐C would be indicated. TG18 proposes that Lap‐C is indicated in Grade III patients with strict criteria. These are that the patients have favorable organ system failure, and negative predictive factors, who meet the criteria of CCI ≤3 and ASA‐PS ≤2 and who are being treated at an advanced center (where experienced surgeons practice). If the patient is not considered suitable for early surgery, TG18 recommends early/urgent biliary drainage followed by delayed Lap‐C once the patient's overall condition has improved. Free full articles and mobile app of TG18 are available at: http://www.jshbps.jp/modules/en/index.php?content_id=47. Related clinical questions and references are also included.
Highlight
Okamoto and colleagues propose in the TG18 that some cases of Grade III acute cholecystitis that satisfy certain strict criteria in terms of predictive factor, Charlson Comorbidity Index, and American Society of Anesthesiologists physical status classification can be treated by laparoscopic cholecystectomy if performed at advanced centers by experienced surgeons.
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