Since the first fertilization of a human egg in the laboratory in 1968, scientific and technological breakthroughs have raised ethical dilemmas and generated policy controversies on both sides of the ...Atlantic. Embryo, stem cell, and cloning research have provoked impassioned political debate about their religious, moral, legal, and practical implications. National governments make rules that govern the creation, destruction, and use of embryos in the laboratory-but they do so in profoundly different ways.
InEmbryo Politics, Thomas Banchoff provides a comprehensive overview of political struggles aboutembryo research during four decades in four countries-the United States, the United Kingdom, Germany, and France. Banchoff's book, the first of its kind, demonstrates the impact of particular national histories and institutions on very different patterns of national governance. Over time, he argues, partisan debate and religious-secular polarization have come to overshadow ethical reflection and political deliberation on the moral status of the embryo and the promise of biomedical research. Only by recovering a robust and public ethical debate will we be able to govern revolutionary life-science technologies effectively and responsibly into the future.
Sex cells Almeling, Rene
2011., 20110821, 2011, 2011-09-20, 20110101
eBook
Unimaginable until the twentieth century, the clinical practice of transferring eggs and sperm from body to body is now the basis of a bustling market. In Sex Cells, Rene Almeling provides an inside ...look at how egg agencies and sperm banks do business. Although both men and women are usually drawn to donation for financial reasons, Almeling finds that clinics encourage sperm donors to think of the payments as remuneration for an easy "job." Women receive more money but are urged to regard egg donation in feminine terms, as the ultimate "gift" from one woman to another. Sex Cells shows how the gendered framing of paid donation, as either a job or a gift, not only influences the structure of the market, but also profoundly affects the individuals whose genetic material is being purchased.
The total number of acquired melanocytic nevi on the skin is strongly correlated with melanoma risk. Here we report a meta-analysis of 11 nevus GWAS from Australia, Netherlands, UK, and USA ...comprising 52,506 individuals. We confirm known loci including MTAP, PLA2G6, and IRF4, and detect novel SNPs in KITLG and a region of 9q32. In a bivariate analysis combining the nevus results with a recent melanoma GWAS meta-analysis (12,874 cases, 23,203 controls), SNPs near GPRC5A, CYP1B1, PPARGC1B, HDAC4, FAM208B, DOCK8, and SYNE2 reached global significance, and other loci, including MIR146A and OBFC1, reached a suggestive level. Overall, we conclude that most nevus genes affect melanoma risk (KITLG an exception), while many melanoma risk loci do not alter nevus count. For example, variants in TERC and OBFC1 affect both traits, but other telomere length maintenance genes seem to affect melanoma risk only. Our findings implicate multiple pathways in nevogenesis.
Technology is changing the manufacturing world. For example, sensors are being used to track inventories from the manufacturing floor up to a retail shelf or a customer’s door. These types of ...interconnected systems have been called the fourth industrial revolution, also known as Industry 4.0, and are projected to lower manufacturing costs. As industry moves toward these integrated technologies and lower costs, engineers will need to connect these systems via the Internet of Things (IoT). These engineers will also need to design how these connected systems interact with humans. The focus of this Special Issue is the smart sensors used in these human–robot collaborations.
The result is a landmark work that will be of interest to readers across the Social Sciences and Humanities as well as Geography and Environmental Studies.
Mediterranean landscape ecology, island cultures and long-term human history have all emerged as major research agendas over the past half-century, engaging large swathes of the social and natural ...sciences. This book brings these traditions together in considering Antikythera, a tiny island perched on the edge of the Aegean and Ionian seas, over the full course of its human history. Small islands are particularly interesting because their human, plant and animal populations often experience abrupt demographic changes, including periods of near-complete abandonment and recolonization, and Antikythera proves to be one of the best-documented examples of these shifts over time. Small islands also play eccentric but revealing roles in wider social, economic and political networks, serving as places for refugees, hunters, modern eco-tourists, political exiles, hermits and pirates. Antikythera is a rare case of an island that has been investigated in its entirety from several systematic fieldwork and disciplinary perspectives, not least of which is an intensive archaeological survey. The authors use the resulting evidence to offer a unique vantage on settlement and land use histories.
Given the importance of affective touch in human interactions, technology designers are increasingly attempting to bring this modality to the core of interactive technology. Advances in haptics and ...touch-sensing technology have been critical to fostering interest in this area. In this survey, we review how affective touch is investigated to enhance and support the human experience with or through technology. We explore this question across three different research areas to highlight their epistemology, main findings, and the challenges that persist. First, we review affective touch technology through the human-computer interaction literature to understand how it has been applied to the mediation of human-human interaction and its roles in other human interactions particularly with oneself, augmented objects/media, and affect-aware devices. We further highlight the datasets and methods that have been investigated for automatic detection and interpretation of affective touch in this area. In addition, we discuss the modalities of affective touch expressions in both humans and technology in these interactions. Second, we separately review how affective touch has been explored in human-robot and real-human-virtual-human interactions where the technical challenges encountered and the types of experience aimed at are different. We conclude with a discussion of the gaps and challenges that emerge from the review to steer research in directions that are critical for advancing affective touch technology and recognition systems. In our discussion, we also raise ethical issues that should be considered for responsible innovation in this growing area.
Human lactation has evolved to produce a milk composition that is uniquely-designed for the human infant. Not only does human milk optimize infant growth and development, it also provides protection ...from infection and disease. More recently, the importance of human milk and breastfeeding in the programming of infant health has risen to the fore. Anchoring of infant feeding in the developmental origins of health and disease has led to a resurgence of research focused in this area. Milk composition is highly variable both between and within mothers. Indeed the distinct maternal human milk signature, including its own microbiome, is influenced by environmental factors, such as diet, health, body composition and geographic residence. An understanding of these changes will lead to unravelling the adaptation of milk to the environment and its impact on the infant. In terms of the promotion of breastfeeding, health economics and epidemiology is instrumental in shaping public health policy and identifying barriers to breastfeeding. Further, basic research is imperative in order to design evidence-based interventions to improve both breastfeeding duration and women’s breastfeeding experience.
How and to what extent have Islamic legal scholars and Middle Eastern lawmakers, as well as Middle Eastern Muslim physicians and patients, grappled with the complex bioethical, legal, and social ...issues that are raised in the process of attempting to conceive life in the face of infertility? This path-breaking volume explores the influence of Islamic attitudes on Assisted Reproductive Technologies (ARTs) and reveals the variations in both the Islamic jurisprudence and the cultural responses to ARTs.
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