Three-dimensional printing is a technology that prints the products layer-by-layer, in which materials are deposited according to the digital model designed by computer aided design (CAD) software. ...This technology has competitive advantages regarding product design complexity, product personalization, and on-demand manufacturing. The emergence of 3D technology provides innovative strategies and new ways to develop novel drug delivery systems. This review summarizes the application of 3D printing technologies in the pharmaceutical field, with an emphasis on the advantages of 3D printing technologies for achieving rapid drug delivery, personalized drug delivery, compound drug delivery and customized drug delivery. In addition, this article illustrates the limitations and challenges of 3D printing technologies in the field of pharmaceutical formulation development.
This review summarizes the application of 3D printing technologies in the pharmaceutical field,with an emphasis on the advantages of 3D printing technologies for achieving rapid drug delivery, personalized drug delivery, compound drug delivery and customized drug delivery. Display omitted
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
Is Agile Cure for Everything Agarwal, Rahul; Singh, Anurupa; Joshi, Ambrish
International journal of engineering & technology (Dubai),
05/2018, Volume:
7, Issue:
1.1
Journal Article
This research paper explores Agile- more in terms of its successes, its limitations, myths around Agile and where it could be the best fit. The paper also envisions to demystify the aura around Agile ...methodology with excerpts gathered from discussions with some of the Agile thought leaders.
Background: In the face of changes taking place as a result of the increasing digitization, automation, and robotization of life and the economy, questions regarding the essence of the functioning of ...modern enterprises and about the emerging new pattern of operation seem to be more and more relevant. Aim of the article: The article focuses on the issues connected with implementation of Industry 4.0 in enterprises, the difficulties involved, and the limitations and challenges that management is facing in the process. Materials and Method: The advantage of the study is its empirical nature. The participants were 39 Industry 4.0 experts from various Polish companies that have participated. At the same time, the aim has been to synthesize theory and practice and to draw attention to potential changes in the area of improvement of the economic results of enterprises that may result from Industry 4.0. Results: The research identified limitations and challenges enterprises may face in connection with the implementation and subsequent stages of development of Industry 4.0 from the practical point of view. Conclusions: Industry 4.0 is an innovative approach to generating a new quality of production. It requires, however, careful and thorough observation of the process already at the preparation stage.
Emergence of the Energy Internet (EI) demands restructuring of traditional electricity grids to integrate heterogeneous energy sources, distribution network management with grid intelligence and big ...data management. This paradigm shift is considered to be a breakthrough in the energy industry towards facilitating autonomous and decentralized grid operations while maximizing the utilization of Distributed Generation (DG). Blockchain has been identified as a disruptive technology enabler for the realization of EI to facilitate reliable, self-operated energy delivery. In this paper, we highlight six key directions towards utilizing blockchain capabilities to realize the envisaged EI. We elaborate the challenges in each direction and highlight the role of blockchain in addressing them. Furthermore, we summarize the future research directive in achieving fully autonomous and decentralized electricity distribution networks, which will be known as Energy Internet.
A history of microarrays in biomedicine Ewis, Ashraf A; Zhelev, Zhivko; Bakalova, Rumiana ...
Expert review of molecular diagnostics,
20/5/1/, Volume:
5, Issue:
3
Journal Article
Peer reviewed
The fundamental strategy of the current postgenomic era or the era of functional genomics is to expand the scale of biologic research from studying single genes or proteins to studying all genes or ...proteins simultaneously using a systematic approach. As recently developed methods for obtaining genome-wide mRNA expression data, oligonucleotide and DNA microarrays are particularly powerful in the context of knowing the entire genome sequence and can provide a global view of changes in gene expression patterns in response to physiologic alterations or manipulation of transcriptional regulators. In biomedical research, such an approach will ultimately determine biologic behavior of both normal and diseased tissues, which may provide insights into disease mechanisms and identify novel markers and candidates for diagnostic, prognostic and therapeutic intervention. However, microarray technology is still in a continuous state of evolution and development, and it may take time to implement microarrays as a routine medical device. Many limitations exist and many challenges remain to be achieved to help inclusion of microarrays in clinical medicine. In this review, a brief history of microarrays in biomedical research is provided, including experimental overview, limitations, challenges and future developments.
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