We, a nurse and a laboratory director, share our experience supporting a research study that employed a digital health application and a rapid test for severe acute respiratory syndrome coronavirus 2 ...and the implications of this approach for health care delivery.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
Featuring contributions from leading scholars in the field, The Handbook of Narrative Analysis is the first comprehensive collection of sociolinguistic scholarship on narrative analysis to be ...published. * Organized thematically to provide an accessible guide for how to engage with narrative without prescribing a rigid analytic framework * Represents established modes of narrative analysis juxtaposed with innovative new methods for conducting narrative research * Includes coverage of the latest advances in narrative analysis, from work on social media to small stories research * Introduces and exemplifies a practice-based approach to narrative analysis that separates narrative from text so as to broaden the field beyond the printed page
Scientists have the tendency to communicate their scientific accounts using linearly structured narratives (Introduction, Methods, Results and Discussion; IMRAD). Likewise, the linear narrative is ...dominant - due to force of habit - when scientists prepare films about their research. Yet, this does not necessarily have to be the case for the new generation of scientists-as-filmmakers, who is trained to appreciate and apply alternative narrative structures. We evaluated the narrative structures of scientists from Swiss universities and research centres. Before the filmmaking courses, 94.1% of participants would use the linear narrative structure in their films, while the remaining participants would use one of the other alternative narrative types. However, after participating in the filmmaking courses, the number of potential users of the linear narrative fell almost 11-fold, and this type of narrative became the least popular. By contrast, after the courses the before-climax-backwards narrative experienced a 79-fold increase in potential use. The parallel, frame and end-backwards narratives had seven-, six- and four-fold increases, respectively. The filmmaking courses also dramatically increased the number of types of narratives that participants would consider using. Filmmaking courses for scientists help scientists-as-filmmakers make a clean break from linear narrative structures in favour of other more varied structures.
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BFBNIB, DOBA, IZUM, KILJ, NUK, PILJ, PNG, SAZU, SIK, UILJ, UKNU, UL, UM, UPUK
Abstract In this article, we discuss a dialogue between narrative theory, reading group practices, and analysis of reading group participants’ experiences. Hanna Meretoja’s theory of narrative agency ...has informed us in developing a new reading group model that aims to enhance the participants’ narrative agency, and, in turn, the analysis of the reading group experiences provides us with new knowledge on the reading group model, as well as on the theoretical approach. We explore narrative agency analysis as a tool to analyze interviews, and our analysis of three participants’ experiences illustrates how narrative agency can manifest itself in various forms. It also demonstrates that the enhanced ability to navigate narrative environments can be highly meaningful on a personal level. The article suggests that, despite its challenges, this kind of research approach, combining theory and practice, enriches and expands the possibilities of literary studies.
Network pharmacology and molecular docking methods were used in the present study to clarify the molecular mechanism of two traditional Chinese medicine prescriptions of climacteric syndrome. Based ...on oral availability and drug similarity, the main active components of Erzhi Pill and Erxian Decoction were screened through the platform of traditional Chinese medicine system pharmacology. The target database of climacteric syndrome was established by using GENECARD, OMIM, PharmGKB, Targets and Drugbank. The “component – target” network diagram was constructed using Cytoscape software (version 3.8.2). Topology analysis, module analysis, and GO and KEGG enrichment analyses were used to explore the core target and action pathway of Erzhi Pill-Erxian Decoction for treating climacteric syndrome of same disease with different treatments. There were 16 active components and 103 corresponding targets found in Erzhi Pill; 69 active components and 121 corresponding targets were found in Erxian Decoction; and 100 potential targets were found in Erzhi Pill and Erxian Decoction. Through network analysis, topology and module analysis, TP53, AKT1, Jun, ESR1, IL1B, CASP3, MMP9, PTGS2, HIF1A, MYC and EGFR could be considered as potential targets of the 2 prescriptions for alleviating climacteric syndrome. The effects of Erzhi pill and Erxian Decoction on climacteric syndrome are mainly in the pathway of lipid and atherosclerosis, AGE-RAGE signaling pathway and PI3K-Akt signaling pathway in diabetic complications. The active components in Erzhi Pill - Erxian Decoction, such as quercetin, show considerable potential as a candidate drug for the treatment of climacteric syndrome.
Since ancient times, acupuncture has been utilized in the treatment of lots of diseases, as a part of Traditional Chinese Medicine. Acupoint embedding (AEM) therapy, known as catgut embedding, is a ...development of acupuncture that consists of inserting catgut or surgical threads into specific acupoints to produce continuous acupoint stimulation based on the theory of Traditional Chinese Medicine. The remaining thread in the acupoint works as a semi-permanent acupuncture needle that results in decreasing the total time of the treatment which is required for continuous manual acupuncture sessions and increasing the treatment efficacy and patients’ satisfaction. In each session of AEM about twenty 1 to 2 cm-long threads—natural origin, synthetic polymer, or bioactive threads—will be inserted at the target acupoints and this process will be repeated every 3 to 4 weeks. Indications of AEM are somehow similar to manual acupuncture including obesity, pain, musculoskeletal inflammations, infertility, etc, and it cannot be performed on pregnant women and pediatrics. AEM demonstrates its therapeutic effects via modulating immune system function, alleviating body inflammatory conditions, affecting the neurohormonal system, and other mechanisms. Subcutaneous indurations, redness, bleeding, hematoma, and bruising are some adverse events reported following the AEM. In conclusion, the scientific literature suggests that AEM is a relatively safe and convenient therapy if performed by a professional skilled practitioner.
