Celem ogólnym artykułu jest opisanie sposobu na kształtowanie kompetencji tekstotwórczej u cudzoziemców uczących się języka polskiego, szczegółowym zaś przedstawienie strategii tworzenia jednej z ...form wypowiedzi pisemnej jaką jest opis (moją szczególną uwagę skupi przedmiot), na przykładzie tekstu literackiego Paryż XX wieku autorstwa Juliusza Verne’a. Studium zbudowano z trzech części: pierwsza zajmuje się teorią struktury opisu, druga umieszcza formę tę w przestrzeni glottodydaktyki polonistycznej, trecia zaś, w postaci aneksu z propozycją ćwiczeń, przestawia konkretne sposoby na kształtowanie umiejętności opisywania rzeczywistości u słuchaczy kursu języka polskiego jako obcego (poziom B2).
W artykule Ekfraza konotacyjna: Batszeba Rembrandta w ujęciu Gustawa Herlinga-Grudzińskiego w centrum uwagi znajduje się problem opisu dzieła sztuki w eseju. Punktem wyjścia do analizy i ...interpretacji deskrypcji artefaktu, tj. Batszeby Rembrandta, jest przybliżenie go z perspektywy historii sztuki. W dalszej części tekst skupia się na werbalnej relacji o obrazie, jaką przynosi esej Gustawa Herlinga-Grudzińskiego Rembrandt w miniaturze. Celem jest przedstawienie konkretnej realizacji formy ekfrazy, a także wskazanie na charakterystyczny tryb widzenia dzieła i pisania o nim – tak w warstwie treściowej, jak językowej. Na końcu pojawia się (wraz z uzasadnieniem) propozycja nazwania omawianego przykładu ekfrazą konotacyjną.
The aim of this article is to compare the modelling of media and memoir coverage of the Brazilian voyage of the “Lviv” in 1923 in two popular illustrated cultural magazines of the interwar period: ...Świat and Tygodnik Ilustrowany. To reconstruct the forms the message, publications from the years 1922–1925 were traced, i.e., those printed before, during, and shortly after the voyage. Using the comparative method and editorial collation, B. Pawłowicz’s and T. Dębicki’s reports published in the magazines were compared with their first book editions. As a result of this contextual analysis, the author shows how the choice of the information strategy pursued by the periodical influenced the modelling of the travel message. This information strategy also determined the reduction of the components presented and led to the creation of two separate stories, bringing people closer to the reality of life in São Vicente, Portugal, or the Brazilian state.
Monogenic obesity can be caused by a mutation in one of the single genes involved in hunger and satiety. The most common mutations affect melanocortin 4 (MC4) followed by the leptin gene and its ...receptor. Leptin receptor (LEPR) gene mutation is an extremely rare endocrine disease characterized by early-onset obesity, hyperphagia in addition to pituitary hormone deficiency, and metabolic abnormalities. We report the case of a 12-month-old male infant born of a non-consanguineous marriage. He presented to us with rapid weight gain from 2 months of age along with hyperphagia. Biochemistry revealed a deranged lipid profile, elevated transaminases, and markedly raised serum leptin levels. On genetic analysis, a novel mutation was detected, which was a homozygous variation In exon 12 of the LEPR gene (chr1:g.65608901G>A) that resulted in the synonymous amino acid change of lysine at codon 584 proximal to donor splice site (p.Lys584). The
in silico
prediction of the variant was ‘damaging’ by MutationTaster2. The mutation was classified as a ‘variant of uncertain significance’ due to a lack of published literature and had to be correlated carefully with the clinical symptoms. It was recommended to do Sanger sequencing of the parents and other family members. However, due to financial constraints, the family could not afford the same. At the time of writing, funds were being arranged for procuring setmelanotide, which is a novel and effective therapy for monogenic obesity due to LepR mutation.
Invasive Listeriosis in Europe – A Case Review Żurawik, Anna; Szczesiul-Paszkiewicz, Paulina; Chmielarczyk, Agnieszka
Postępy mikrobiologii,
03/2024, Volume:
63, Issue:
1
Journal Article
Peer reviewed
Open access
bacilli are a known cause of non-invasive gastrointestinal listeriosis with diarrhea, less frequently they cause invasive infections: meningitis and encephalitis, bacteremia and its complications: ...endocarditis, intraocular inflammation of the eye and others. The risk of human infection is mainly associated with consuming food contaminated with these bacteria. According to the European Food Safety Authority (EFSA), infections with
etiology caused the highest hospitalizations and deaths among zoonotic diseases reported in 2022. A report by the European Center for Disease Prevention and Control (ECDC) reported 0.44 cases of listeriosis per 100,000 population in 2021, with the highest incidence rate for people over 64 years old at 1.7.
The study aimed to review and describe cases of invasive listeriosis diagnosed in adult patients in Europe between 2010 and 2023. Fifty-two cases of the disease were included, of which 19 were meningitis, 13 showed bacteremia, nine were associated with endocarditis and 10 with intraocular inflammation. One case had a clinical form of hepatitis. Only seven cases of
infection were related to consuming contaminated food. Eleven cases ended in the death of patients.
Invasive listeriosis is a difficult-to-treat infection with a significant mortality rate. It requires decisive action by monitoring the prevalence and extent of food contamination with these microorganisms and preventing epidemic outbreaks. Research on listeriosis should focus on improving the clinical treatment of severe cases of infection and studying the complex mechanisms of their pathogenesis.
Turner syndrome (TS) is a genetic defect accompanied by gonadal dysgenesis, short stature, characteristic dysmorphic features, congenital heart and kidneys defects, and other diseases. One of the ...less common are vascular malformations in the gastrointestinal (GI) tract. They are asymptomatic in some patients, but can also cause GI bleeding. We present a description of a 12-year-old patient with TS and vascular malformations in the GI tract who was admitted to the hospital because of recurrent microcytic anemia. At the age of 15, she started estrogen therapy due to hypogonadism. Since then, the bleeding has stopped and the number of malformations on follow-up colonoscopy has been significantly decreased. In TS patients with iron deficiency anemia, the differential diagnostics should include vascular defects in the GI. There are evidences, that estrogen therapy may limit the number of lesions and reduce the risk of bleeding.
Everything Must Go Zaia, Shana
Altorientalische Forschungen,
06/2021, Volume:
48, Issue:
1
Journal Article
Peer reviewed
Abstract
This paper presents a study of YOS 17, 360, a collection of 30–33 administrative records from the Eanna temple in Uruk that are dated to Nabû-kudurrī-uṣur (Nebuchadnezzar) II’s 14
th
year. ...The first few columns contain transactions concerning gold, while the rest are largely related to prebendary payments. In addition to providing an edition of YOS 17, 360 and related texts, this study seeks to understand why these particular transactions were collected and what insight it gives us into the historical circumstances. The evidence suggests that Eanna experienced a financial crisis at this time, during which it sold off its assets and had difficulties paying its priests. The cause of the crisis seems to have been royal demands put on the temple to provide money and manpower in support of the king’s building and/or military endeavors, possibly including Babylonian movements into the Levant and resulting clashes with Egypt.
Everything Must Go Zaia, Shana
Altorientalische Forschungen,
06/2021, Volume:
48, Issue:
1
Journal Article
Peer reviewed
Open access
This paper presents a study of YOS 17, 360, a collection of 30–33 administrative records from the Eanna temple in Uruk that are dated to Nabû-kudurrī-uṣur (Nebuchadnezzar) II’s 14
year. The first few ...columns contain transactions concerning gold, while the rest are largely related to prebendary payments. In addition to providing an edition of YOS 17, 360 and related texts, this study seeks to understand why these particular transactions were collected and what insight it gives us into the historical circumstances. The evidence suggests that Eanna experienced a financial crisis at this time, during which it sold off its assets and had difficulties paying its priests. The cause of the crisis seems to have been royal demands put on the temple to provide money and manpower in support of the king’s building and/or military endeavors, possibly including Babylonian movements into the Levant and resulting clashes with Egypt.
Newborn screening for congenital hypothyroidism (CH) has been highly effective in preventing devastating neurodevelopmental and physical sequelae in affected infants. We report a case of an ectopic ...thyroid gland located in the submandibular area detected at the age of 3 months, which was missed by congenital hypothyroidism screening test based on twice-repeated TSH measurement in dried blood spots. The diagnosis of subclinical hypothyroidism was confirmed on the basis of blood test performed in the endocrine clinic: TSH 26.3 µIU/ml (N: < 10 µIU/ml), with FT4 14.7 pmol/l (N: 10-25 pmol/l) and fT3 6.9 pmol/l (N: 3-8 pmol/l). Ultrasonography and scintigraphy revealed ectopically located thyroid tissue in the sublingual area. In the case of doubtful results of a neonatal screening test or in any case of suspected congenital hypothyroidism, the diagnosis should be supplemented with ultrasound examination of the neonate's neck and followed by scintigraphy if necessary.