A one-of-a-kind presentation of the major achievements in statistical profile monitoring methods Statistical profile monitoring is an area of statistical quality control that is growing in ...significance for researchers and practitioners, specifically because of its range of applicability across various service and manufacturing settings. Comprised of contributions from renowned academicians and practitioners in the field, Statistical Analysis of Profile Monitoring presents the latest state-of-the-art research on the use of control charts to monitor process and product quality profiles. The book presents comprehensive coverage of profile monitoring definitions, techniques, models, and application examples, particularly in various areas of engineering and statistics. The book begins with an introduction to the concept of profile monitoring and its applications in practice. Subsequent chapters explore the fundamental concepts, methods, and issues related to statistical profile monitoring, with topics of coverage including: Simple and multiple linear profiles Binary response profiles Parametric and nonparametric nonlinear profiles Multivariate linear profiles monitoring Statistical process control for geometric specifications Correlation and autocorrelation in profiles Nonparametric profile monitoring Throughout the book, more than two dozen real-world case studies highlight the discussed topics along with innovative examples and applications of profile monitoring. Statistical Analysis of Profile Monitoring is an excellent book for courses on statistical quality control at the graduate level. It also serves as a valuable reference for quality engineers, researchers and anyone who works in monitoring and improving statistical processes.
Recent studies in the field of laboratory medicine revealed that pre analytical phase is the error prone area and source of 60-65% laboratory errors. The satisfactory fulfillment of requirements of ...ISO 15189:2012 is assuring Internal Quality Control but to assess such activity an external assessment program is necessary. An external assessment program (PRE-EQC) has been started and findings of every performance is being send to the participants along with the results. The PRE-EQC program is a simultaneous Proficiency Testing scheme. Pooled samples are collected, preservative added to the sample. The analytes to be tested are tested by the PRE-EQC Coordinator. Samples are sent to the participants within PT provider's time frame. The method is a 4 step method: A set of questionnaires on sample handling. Measurement of one/two analytes to check integrity of analytes. Simulation of errors. Coordinators feedback along with assessment sheet. The assessment sheets are sent to the participants by e mail. PT provider writes comment so that participant can locate the area requires continuous monitoring. The basic rule of PRE-EQC is to create the program in such a manner which can be monitored without remaining present in the participant laboratory as direct act of monitoring is more audit than external assessment. The questionnaire and simulation of error has been done in such manner so that it reflect the status of the laboratory.
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All providers of laboratory medicine services aim to provide a 'high quality' service but our understanding of what this means is variable. The IFCC has developed a 'quality ladder' to illustrate the ...stages of quality improvement. The aim of all laboratory specialists should be continuous quality improvement, effectively climbing the rungs of the quality ladder. The top of the ladder is reached through laboratory accreditation against the international standard ISO 15189:9019. Continuous quality improvement requires an active programme of quality management. This involves a continuous series of internal audits against locally established quality standards supplemented by benchmarking against external standards of performance. Documentation and document control are essential internal elements of quality management. External standards include: staff training and qualifications; performance in external quality assurance programmes; user satisfaction surveys; and, ultimately, full accreditation by external assessors against ISO 15189:9019. Everyone working in a clinical laboratory should contribute to continuous quality improvement. The results from laboratory medicine investigations inform a high percentage of all clinical decisions. Therefore, provision of a high quality service is of critical importance to patients, both in terms of patient safety and improving quality outcomes. In an increasingly litigious world avoidable quality failures in the provision of laboratory medicine services are unacceptable to patients and the public. Laboratory directors are being asked to provide evidence of their quality standards of performance. Contracts for service provision, clinical trials and research programmes are becoming conditional on provision of that evidence.
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15.
ACBI/CMC EQAS--QUO VADIS? Geethanjali, F.S; Selvakumar, R
Indian journal of clinical biochemistry,
05/2022, Volume:
27, Issue:
S1
Journal Article
Peer reviewed
Objective: The objective of this retrospective study is to evaluate the usefulness of the ACBI/CMC EQAS program in the overall performance of Indian Laboratories as well as individual labs in ...different categories over the years. It is the journey of our National EQAS over the past decade. Method: The awareness of the Indian labs towards quality assurance is evaluated based on the number of participants, the response in submitting results, annual evaluation and the trend in methods selection. Similarly few labs form each category such as lab size (number of parameters done), type (public/private) and few labs at random were selected and their performance is evaluated over the past 10 years. Results: The awareness of Quality assurance in India has tremendously increased and is reflected by a 100% increase in the number of participants over the past ten years. The randomly selected labs showed decreased OMVIS which is indirectly proportional to their performance. Conclusion: It was during this past 10 years, lot of changes took place in the ACBI/CMC EQAS, i.e., change over form bovine sera to human sera, liquid samples to lyophilised samples, introducing immunoassay program etc. This study shows how the Indian laboratories have improved their performance as well as their awareness towards the QA-concept. It is very encouraging to note that the concept of EQAS is well accepted and appreciated by majority of laboratories and thus paving the way towards international standards.
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Outlines the correct procedures for doing FMEAs and how to successfully apply them in design, development, manufacturing, and service applications There are a myriad of quality and reliability tools ...available to corporations worldwide, but the one that shows up consistently in company after company is Failure Mode and Effects Analysis (FMEA). Effective FMEAs takes the best practices from hundreds of companies and thousands of FMEA applications and presents streamlined procedures for veteran FMEA practitioners, novices, and everyone in between. Written from an applications viewpoint—with many examples, detailed case studies, study problems, and tips included—the book covers the most common types of FMEAs, including System FMEAs, Design FMEAs, Process FMEAs, Maintenance FMEAs, Software FMEAs, and others. It also presents chapters on Fault Tree Analysis, Design Review Based on Failure Mode (DRBFM), Reliability- Centered Maintenance (RCM), Hazard Analysis, and FMECA (which adds criticality analysis to FMEA). With extensive study problems and a companion Solutions Manual, this book is an ideal resource for academic curricula, as well as for applications in industry. In addition, Effective FMEAs covers: * The basics of FMEAs and risk assessment * How to apply key factors for effective FMEAs and prevent the most common errors * What is needed to provide excellent FMEA facilitation * Implementing a "best practice" FMEA process Everyone wants to support the accomplishment of safe and trouble-free products and processes while generating happy and loyal customers. This book will show readers how to use FMEA to anticipate and prevent problems, reduce costs, shorten product development times, and achieve safe and highly reliable products and processes.
The accumulation of damaged and aggregated proteins is a hallmark of aging and increased proteotoxic stress. To limit the toxicity of damaged and aggregated proteins and to ensure that the damage is ...not inherited by succeeding cell generations, a system of spatial quality control operates to sequester damaged/aggregated proteins into inclusions at specific protective sites. Such spatial sequestration and asymmetric segregation of damaged proteins have emerged as key processes required for cellular rejuvenation. In this review, we summarize findings on the nature of the different quality control sites identified in yeast, on genetic determinants required for spatial quality control, and on how aggregates are recognized depending on the stress generating them. We also briefly compare the yeast system to spatial quality control in other organisms. The data accumulated demonstrate that spatial quality control involves factors beyond the canonical quality control factors, such as chaperones and proteases, and opens up new venues in approaching how proteotoxicity might be mitigated, or delayed, upon aging.
Damaged and aggregated proteins accumulate during aging and increased proteotoxic stress. This review describes the spatial and temporal quality control systems that operate to limit toxicity and the inheritance of damage by succeeding cell generations.
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In the present day deregulated power market electric power quality issues have become great concerns of utilities, end users and manufacturers. Worldwide researches are going on to address those ...issues. Electric Power Quality has evolved from the researches carried out by the authors. The key features of the book can be highlighted as follows: the contents focuses, on one hand, different power quality issues, their sources and effects and different related standards, which are required for students, researchers and practising engineers and, on the other hand, measurement techniques for different power quality parameters, the content level is designed in such a way that the concepts of different power quality issues in modern power system are built up first, followed by some existing and new measurement methods. This content should attract the students, researchers and practising engineers, the predominant features are Lucid but concise description of the subject, detailed new measurement techniques and Electric Power Quality is intended for graduate, postgraduate and researchers as well as for professionals in the related fields. At the end, a chapter has been added which deals with a concept of generation of harmonics in a power system and its components.
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