Engine noise, as a source of sound pollution for humans and the environment, can be reduced by designing a high-performance muffler. This study presents a novel, organized design process of that ...muffler for the KTM390 engine as a case study. The acoustic simulation analysis is performed in COMSOL software and aerodynamic analysis is performed in ANSYS Fluent. The features of the muffler considered in this designing process are the overall length of the muffler, the presence of baffles and related parameters (baffle distance, baffle hole diameter, and baffle hole offset), and the effects of extended tubes. In order to evaluate the acoustic performance of the muffler, an objective function has been defined and measured on two frequency ranges, 75–300 Hz and 300–1500 Hz. For evaluating the aerodynamic performance of that, the amount of backpressure is analyzed to achieve a maximum of 3.3 kilopascals for this muffler. The selection of the appropriate parameters includes comparing the resulting transmission loss curves and quantitative evaluation of objective functions (for transmission loss) and backpressure. This organized design process (i.e., tree diagram) leads to an increase in the efficiency of designing mufflers (for example, 41.2% improvement on backpressure).
OBJECTIVE Approximately half of glioblastoma (GBM) cases develop in geriatric patients, and this trend is destined to increase with the aging of the population. The optimal strategy for management of ...GBM in elderly patients remains controversial. The aim of this study was to assess the role of surgery in the elderly (≥ 65 years old) based on clinical, molecular, and imaging data routinely available in neurosurgical departments and to assess a prognostic survival score that could be helpful in stratifying the prognosis for elderly GBM patients. METHODS Clinical, radiological, surgical, and molecular data were retrospectively analyzed in 322 patients with GBM from 9 neurosurgical centers. Univariate and multivariate analyses were performed to identify predictors of survival. A random forest approach (classification and regression tree CART analysis) was utilized to create the prognostic survival score. RESULTS Survival analysis showed that overall survival (OS) was influenced by age as a continuous variable (p = 0.018), MGMT (p = 0.012), extent of resection (EOR; p = 0.002), and preoperative tumor growth pattern (evaluated with the preoperative T1/T2 MRI index; p = 0.002). CART analysis was used to create the prognostic survival score, forming six different survival groups on the basis of tumor volumetric, surgical, and molecular features. Terminal nodes with similar hazard ratios were grouped together to form a final diagram composed of five classes with different OSs (p < 0.0001). EOR was the most robust influencing factor in the algorithm hierarchy, while age appeared at the third node of the CART algorithm. The ability of the prognostic survival score to predict death was determined by a Harrell’s c-index of 0.75 (95% CI 0.76–0.81). CONCLUSIONS The CART algorithm provided a promising, thorough, and new clinical prognostic survival score for elderly surgical patients with GBM. The prognostic survival score can be useful to stratify survival risk in elderly GBM patients with different surgical, radiological, and molecular profiles, thus assisting physicians in daily clinical management. The preliminary model, however, requires validation with future prospective investigations. Practical recommendations for clinicians/surgeons would strengthen the quality of the study; e.g., surgery can be considered as a first therapeutic option in the workflow of elderly patients with GBM, especially when the preoperative estimated EOR is greater than 80%.
Zusammenfassung
In stochastischen Situationen mit zwei dichotomen Merkmalen erlauben weder die schulüblichen Baumdiagramme noch Vierfeldertafeln die simultane Darstellung sämtlicher in der Situation ...möglicher Wahrscheinlichkeiten. Das im vorliegenden Beitrag vorgestellte Netz hat die Kapazität, alle vier möglichen Randwahrscheinlichkeiten, alle vier Schnittwahrscheinlichkeiten sowie alle acht bedingten Wahrscheinlichkeiten
gleichzeitig
darzustellen. Darüber hinaus ist – aufgrund der Knoten-Ast-Struktur des Netzes – die simultane Darstellung von Wahrscheinlichkeiten
und
absoluten Häufigkeiten mit dieser Visualisierung ebenfalls möglich. Bei der sukzessiven Erweiterung des typischen Baumdiagramms zunächst zum Doppelbaum und schließlich zum Netz sinkt der Inferenzgrad (d. h. weniger kognitive Schritte sind erforderlich) z. B. für Fragen nach bedingten Wahrscheinlichkeiten, aber gleichzeitig steigt die Komplexität der Darstellung und somit die extrinsische kognitive Belastung. Im vorliegenden Artikel erfolgt zunächst ein theoretischer Vergleich dieser Knoten-Ast-Strukturen. Eine anschließende Studie illustriert, dass sich die sukzessive Erweiterung bereits vollständig ausgefüllter Diagramme positiv auf die Performanz von
N
= 269 Schülerinnen und Schülern auswirkt. Obwohl
Häufigkeitsdoppelbäume
und
Häufigkeitsnetze
den Schülerinnen und Schülern gänzlich unbekannt waren, unterstützten diese Visualisierungen die Schülerinnen und Schüler bei der Bearbeitung der Aufgaben am meisten.
Full text
Available for:
EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
In this paper, they are presented the defects of products which are obtained byforging and actions that can be taken to reduce these defects. They are highlighted the relationsbetween the proposed ...target of reducing defects and the actions which are identified to achieve the objective.
Full text
Available for:
IZUM, KILJ, NUK, PILJ, PNG, SAZU, UL, UM, UPUK
Pada masa sekarang hampir semua aplikasi yang memiliki fitur navigasi menggunakan model tree diagram dengan indented layout, yaitu tree yang terekspansi ke kanan secara terus-menerus untuk ...menunjukkan hubungan antara file induk dengan file anak. Contoh yang paling mudah dan banyak dikenal orang adalah sistem explore folder pada Windows.
In this paper the authors present a study on the use of the tree diagram to solve a quality problem in a chemical laboratory. The study aims to identify actions/measures that ensure elimination of ...sources of errors that cause non-quality problems in analyzes performed in a chemical laboratory. Several measures have been identified that have been grouped into four categories corresponding to four specific objectives. There was a relatively complex 4-level tree diagram. The specified tree chart is useful for organization management and staff in the chemical laboratory to prevent and eliminate nonconformities and generally to improve the quality of the deployed activities.
Romanian healthcare confronts with several issues remained still unsolved. One of the mainissues is bureaucracy. In our country bureaucracy finds a place in almost every public sector,especially in ...healthcare. Doctors have to complete daily papers over papers, to hand them to theNational Insurance House and then, in the rest of the time, to practice their job. Unfortunately, thetime for medicine is limited because of the several situations that must be completed monthly. Our paper tries to analyze the main problem, along with its root causes, in order to proposeviable solutions that could be adopted so our healthcare system could be among the otherEuropean healthcare systems.
In this study, a multivariate analysis of morphological and physiological characteristics was performed on clinically healthy rams from six breeds (Santa Ines, Bergamasca, Dorper, Texel, Ile de ...France and Hampshire Down) to determine if these characteristics were able to separate and determine the most important variables in the differentiation of breeds for heat adaptation. To characterize the thermal environment, mean temperature was 23°C and relative humidity ranged between 30.6-55.6%. Morphological and physiological data were subjected to multivariate statistical tests including principal components (PRINCOMP), clustering (CLUSTER), discriminant (DISCRIM), step-by-step (STEPDISC) and canonical (CANDISC) analyses, using the Statistical Analysis System (SAS®). A multiple analysis of variance (MANOVA) was carried out with the variables defined as important by the discriminant analysis. The principal components analysis for biometric characteristics and scrotum-testicle, for physiological characteristics and body temperature as well as the characteristics of the skin and hair explained 60, 70 and 67 % of the total variation, respectively. The dendrogram showed a clear separation between the breeds studied and the existence of two distinct groups, one formed by the Texel and the other by the other breeds, considering all the characteristics used in the study. The most useful morphological parameters to explain heat tolerance were diameter of hair, layer thickness of hair at withers, 12th thoracic vertebra and rump, withers height, thoracic and scrotal circumferences, body weight, anterior and posterior shin perimeters, hair and epidermis brightness as well as the content of red and yellow in the epidermis. Among physiological characteristics, respiratory rate was better than rectal temperature and heart rate to explain changes caused by thermal stress. From the multivariate and variance analyzes it can be concluded that the Santa Ines breed was the most tolerant to heat stress as it presented a highly pigmented epidermis, a shorter hair of larger diameter, the lower layer thickness of hair at withers, 12th thoracic vertebra and rump, the lower temperatures in the testicle and at the 12th thoracic vertebra as well as the lower respiratory rate and rectal temperature value.
Fault diagnosis of automobile systems is critical, as it adds-up to repair and maintenance time. It is, therefore, desired to make it efficient and effective. One of the conventional approaches is to ...use the fault tree diagram. But this approach is inadequate with its implicit system structure. Structure of the system means system elements and their interrelations. To alleviate this limitation, a new approach is suggested wherein the structure is in-built, i.e. incorporated explicitly, through digraph modeling that employs a systems approach of graph theory. A system digraph is developed, considering relationships among input and output parameters of subsystems/components of the automobile system in normal and failed conditions. Fault tree of a failure symptom that represents abnormality or a breakdown of the automobile system is obtained from the system digraph. The novelty is extension of the structural approach to automobile systems using digraph model, which has been successfully applied to chemical and process systems. Step-by-step methodology of the structural approach is presented. Its two main two steps are Steps 1 and 2, i.e. ‘Development of Fault tree diagram’ and ‘Diagnosis of fault using the tree diagram’, respectively. The suggested approach is illustrated for hydraulic power steering, an automobile system that is fitted on all current automobiles and particularly, in special purpose vehicles like heavy-duty trucks, earthmovers, dumpers, etc. The suggested approach guides how to diagnose root causes of a fault. The approach is not only helpful to maintenance personnel in effective diagnosis but also in guiding designers in development of reliable automobile systems, accident investigations of automobiles, etc.
Full text
Available for:
EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OBVAL, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ