Provider: - Institution: - Data provided by Europeana Collections- Obelisc, realizat din piatră de Albești, de secțiune dreptunghiulară. Este fixat pe un soclu, în trepte, din beton. Deasupra ...capitelului este fixată o cruce sigilată („IS, HS, NI, KA”). Pe fața principală a obeliscului este un basorelief reprezentând un soldat în poziție de tragere, un tun și frunze de stejar. Inscripțiile sunt incizate și conturate cu vopsea neagră. Înălțime (h) monument: aproximativ 4m.- Mențiuni despre monument: Stare bună de conservare.- Inscripții pe monument: Pe fața principală: „1916-1919”, „1941-1945” NUME DE EROI (35) din Primul Război Mondial Pe postament: „S'A RIDICAT/ ACEST MONUMENT DE LOCUITORII COMU/ NEI CIUMEȘTI ÎN AMINTIREA SCUMPĂ/ ȘI VEȘNICĂ A CELOR MAI BUNI DINTRE/ EI CE S-AU JERTFIT PE CÎMPUL DE/ ONOARE PENTRU ȚARĂ/ 15 AUGUST 1945” Pe latura sudică: „1941-1945”, „1877” NUME DE EROI din Al Doilea Război Mondial (14) NUME DE EROU din Războiul de Independență (1) Pe postament: „ST. ARGANINI, PITEȘTI” Pe latura nordică: „1941-1945” NUME DE EROI (15) din Al Doilea Război Mondial- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Provider: - Institution: - Data provided by Europeana Collections- Monumentul este de tip obelisc, cu o cruce în partea superioară. Pe suportul său e sculptat un pahar cu semnul decorației „Crucea de ...Război”. Coborând, urmează frontonul decorat cu o palmetă centrală și ramuri de stejar, și cu un motiv zimțat, în chip de cornișă. Principalul ornament al obeliscului îl constituie un medalion cu palmetă, ramuri înflorite și aceeași decorație „Crucea de Război”. Trecerea la treptele din beton se face printr-un volum paralelipipedic din marmură.- Mențiuni despre monument: Monumentul are o stare bună de conservare.- Inscripții pe monument: Pe față: „ÎNTRU VEȘNICA AMINTIRE A SĂTENILOR-OSTAȘI DIN BOLINTINU DIN DEAL MORȚI ÎN LUPTELE DIN RĂZBOIUL PENTRU ÎNTREGIREA NEAMULUI 1916-1918 ȘI A RIDICAT ACEST MONUMENT” „RIDICAT ÎN 1919/ DIN DONAȚII” „EROILOR/ ORI UNDE VI-I MORMÂNTUL, VI-I GLORIA CUNUNĂ VOI ȚĂRII V'AȚI DAT VIAȚA ȘI DACIA STRĂBUNĂ RE'NVIE BRAȚU VOSTRU VITEAZ-I-A FOST DESTIN” „PLUGARI PE-OGORUL VOSTRU, OSTAȘI SUB STEAGUL ȚĂRII,/ NEBIRUIȚI ÎN LUPTE, EROI AI APĂRĂRII/ EROI PE VECI RĂMÂNEȚI SĂTENI DIN BOLINTIN/ DIN BOLINTINUL/ CURG VEACURILE-N VREME SE SCHIMBĂ OMENIREA/ ISTORIA SCULPTEAZĂ ÎN MARMURĂ AMINTIREA/ ȘI LOCURI, FAPTE, NUME RĂMÎN SPRE A TRĂII/ ETERNITATEA TINDE ASUPRĂ-LE SĂ ȚINĂ/ LUMINĂ DIN NESTINSA IZBÎNZILOR LUMINĂ/ ÎN EA VOI VĂ CUPRINDEȚI ȘI PILDĂ-N VECI VEȚI FI!/ DIN DEAL/ NU MAI SUNTEȚI ACUM ÎN SAT LA NOI ȘI-N VIAȚĂ/ DAR VĂ VEDEM AIEVEA ÎN ZĂRI FĂRĂ DE CEAȚĂ/ ÎNCONJURAȚI DE RAZE DE SOARE CE NU PIER/ VOI, PENTRU SATUL NOSTRU ȘI-NTREAGA ROMÂNIE/ SÎNTEȚI DE TOTDEAUNA ONOARE ȘI MÎNDRIE,/ EROI SFINȚIȚI DE ȚARĂ, DE NEAMU-NTREG DE CER./ N. RADULESCU NIGER” „COMITETUL/ PREOT ECON STEFAN POPESCU INIȚIATORUL D. NIȚESCU ÎNVĂȚĂTOR - NICOLAE ST. POPESCU NOTAR C-TICĂ DANCIU COMERCIANT - GH. N. POPESCU PRIMAR” Lateral dreapta: „EROII DIN RĂZBOIUL REÎNTREGIRII/ 1941” și lista cu numele eroilor; „FONDAȚI DONATĂ DE D-UL INGINER MINCU ȘI LUCRATĂ DE STANCU STEFĂNESCU, MITU GH. ȘI ION C. NENCIU/ ACEST LOC E DONAT DE PARASCHIV ION” Pe spate: „OFIȚERI 1916-1918” și lista cu numele eroilor; Lateral stânga: „N. LAMBADITIS/ SCULPT. BUC.”- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
The integration of remote sensing, spectral measurements and field verification helped in discriminating new iron occurrences hosted in the metavolcanic rocks at Wadi Karim and Gabal El-Hadid areas ...in the Central Eastern Desert (CED) of Egypt. The iron host rocks were carefully recognized through different image processing techniques that were applied on Landsat-8 satellite image data with the implementation of the spectral signatures of the various iron minerals and host rocks. The detected iron ore is found in the form of Banded Iron Formation (BIF), veins and lenses of varied thicknesses ranging from a few centimetres to 5 m. They are composed mainly of magnetite and hematite, as well as accessories of aluminium, iron silicates and quartz. Moreover, the structure controls on iron ore occurrences were also illustrated in the investigated areas. The alignment of the iron forms with the primary and secondary structural planes of their host rocks may indicate the origin and mode of occurrence of the explored iron ore, as contemporaneous and syngenetic deposition with the solidification of the host metavolcanics. Several remote sensing techniques including Crosta principal component analysis (CPCA), constrained energy minimization (CEM) supervised classification technique and a newly proposed Landsat-8 band ratio (band6/band2) were applied for discriminating the iron-rich localities within the studied areas. These techniques showed high efficiency and applicability in the accurate delineation of the iron-enriched areas; this was validated through the field study.
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EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, KILJ, KISLJ, MFDPS, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
In this thesis we investigated the possibilities of translating the preposition um from German to Serbian. While reading a translated text, we usually do not ask questions about the translation ...equivalents. But how many are there actually? Do they have to be the same part of speech? This work has shown the most common and popular solutions, but without neglecting the rare ones. It was proven that the most common translation equivalent of the preposition um is also a preposition in Serbian, namely the preposition u. In addition, there are other prepositions and structures, as well as other parts of speech. For some examples it was not possible to identify an equivalent. The method used in this article is contrastive analysis.
The virus-like drug conjugate belzupacap sarotalocan (AU-011), currently under clinical investigation for first-line treatment of primary uveal melanoma (UM), shows enhanced tumor specificity by ...targeting heparan sulfate proteoglycans (HSPG). Such a treatment may potentially lead to systemic immune responses. We studied the potential of AU-011 treatment to induce immunogenic cell death as the first step to induce systemic immunity.
We determined binding and uptake of AU-011 in ten primary and metastatic UM cell lines. The subcellular location of AU-011 was assessed by fluorescence microscopy. Following light activation (wavelength 690 nm) of AU-011, the half-maximal effective concentration (EC50) of AU-011 treatment and exposure of damage-associated molecular patterns (DAMPs) were assessed using flow cytometry. DAMPs were measured by RNAseq.
Fluorescence microscopy revealed most of the AU-011 was present in the cytoplasm. AU-011 binding and uptake by UM cells increased over time, with a lower uptake in BAP1-negative than in BAP1-positive cell lines. AU-011 activation induced cell death across all UM cell lines with EC50 values at picomolar concentrations. The AU-011 concentration and total light dose (J/cm2) were the most important parameters for the observed cytotoxicity. Finally, light-activated AU-011 induced exposure of DAMPs calreticulin (CRT) and HSP90. CRT exposure by light-activated AU-011 as well as CRT RNA exposure were lower in BAP1-negative compared to BAP1-positive UM cell lines.
AU-011 treatment at low picomolar range induces immunogenic cell death in all 10 UM cell lines. The in vitro cytotoxicity was accompanied by exposure of DAMPs (HSP90 and CRT), suggesting AU-011 may contribute to the development of systemic immunity and be a suitable candidate for combination with immunotherapy in vivo. AU-011 treatment was more effective against BAP1-positive cell lines, with a lower EC50 and higher CRT exposure.
Low-protein diets promote metabolic health in humans and rodents. Despite evidence that sex and genetic background are key factors in the response to diet, most protein intake studies examine only a ...single strain and sex of mice. Using multiple strains and both sexes of mice, we find that improvements in metabolic health in response to reduced dietary protein strongly depend on sex and strain. While some phenotypes were conserved across strains and sexes, including increased glucose tolerance and energy expenditure, we observed high variability in adiposity, insulin sensitivity, and circulating hormones. Using a multi-omics approach, we identified mega-clusters of differentially expressed hepatic genes, metabolites, and lipids associated with each phenotype, providing molecular insight into the differential response to protein restriction. Our results highlight the importance of sex and genetic background in the response to dietary protein level, and the potential importance of a personalized medicine approach to dietary interventions.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
Magnetic methods of exploration have proved to be efficient and have potential in the gold mineralization industry. New magnetic processing technologies aid in improving the process of interpretation ...and gold opportunity identification. In this work, we show the possible application of combined digital magnetic filters to explore new gold mineralization localities with application to a well-known Au mineralization zone. Um Garayat (UG) region, southeastern desert, Egypt, is an ancient example of a potential area for gold mining. Modern analysis showed that other types of mineral concentrations are present. So, exploiting the magnetic signature of the area for future investment is of great interest. The old UG gold mine is characterized by volcanic and tectonic features such as faulting and folding that affect the arc sedimentary rock sequence of repeated deformation stages. A thorough geophysical effort has been carried out around the old gold mine in the UG area to explore the extension of mineralized ore deposits. A detailed geophysical survey using magnetics was carried out in this study together with the available aeromagnetic data. Field data sets on appropriate sites were measured, processed, and evaluated by suitable software. High magnetic anomalies were detected based on grid filter analysis and contact occurrence maps as marked as possible ore deposits after satisfying the geologic conditions for gold formation. An integrated understanding of attained results revealed that the new possible ore deposits are related directly to fault and fracture zones in the shape of lenses of variable thickness in this zone. Results show that newly detected mineral occurrences in the UG area are also controlled by major faults and hydrothermal solution enrichment along fault zones at a depth ranging from 20 to 70 m. Favorable fault/joint mineralized places were located. The relationship between the Au-quartz vein's strike direction compared with magnetic anomaly lineament analysis was studied. Search for new sources of Au and other mineral deposits in addition to quartz veins is needed as pockets of accumulated mineral-rich rock fragments are deposited in drainage wadis and fault/joint zones because of hydrothermal solution enrichment.
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DOBA, EMUNI, FIS, FZAB, GEOZS, GIS, IJS, IMTLJ, IZUM, KILJ, KISLJ, MFDPS, NLZOH, NUK, OILJ, PILJ, PNG, SAZU, SBCE, SBJE, SBMB, SBNM, UILJ, UKNU, UL, UM, UPUK, VKSCE, ZAGLJ
•Khur Um-Safi serpentinites were derived from a depleted mantle peridotite source.•They represent mantle residues from 15 to 20 % melting of spinel peridotite.•This range of melt extraction is ...consistent with the typical range of SSZ peridotite.•They formed under QFM + 1 buffer suggesting evolution under a more oxidizing regime.•They show affinity to modern fore-arc basin system.
Serpentinites in the Eastern Desert of Egypt are the most distinctive lithological unit in the Arabian–Nubian Shield (ANS) ophiolite sequence which associated with major suture zones. Khor Um-Safi (KUS) serpentinites represent dismembered fragments of ophiolitic rocks located in the central Eastern Desert (CED) of Egypt.
KUS serpentinites exhibit affinity to the typical metamorphic peridotites with harzburgitic protolith compositions. Their opaque mineral assemblage (pentlandite, heazlewoodite and magnetite) is similar to that observed in oceanic serpentinites and implies serpentinization under highly reducing conditions. They have refractory major element compositions with Al2O3 contents comparable to oceanic and active margin peridotites as well as Pan-African serpentinites. The Cr and TiO2 contents reflect evolution within a supra-subduction zone (SSZ) environment. This implication is confirmed by the Al2O3/SiO2 and MgO/SiO2 ratios which akin to ANS ophiolitic peridotites in fore-arc setting. Their enrichment in compatible trace elements (Cr, Ni and Co) reveals a depleted mantle peridotite protolith.
Modelling trace elements indicates that they represent the mantle residues from 15 to 20 % melting of spinel peridotite at oxygen fugacity conditions of the QFM + 1 buffer. This range of melt extraction is consistent with the typical range of SSZ peridotite. Oxygen fugacity estimation suggests evolution under more oxidizing regime similar to modern fore-arc basin system. Moreover, this implication indicates that the KUS mantle represents arc lithosphere interacted with arc melt.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
The Late Neoproterozoic rare metal-bearing granite of Um Naggat pluton records deuteric and magmatic-hydrothermal fluid activities that culminated in overlapping sequential metasomatic alterations. ...The pluton is petrographically discriminated into subsolvus biotite, hypersolvus alkali-feldspar, and subsolvus albite granites. The residual fluid interacted and re-equilibrated with the mica and feldspars. Two phases of albitization, greisenization, chloritization and hematitization, and one phase of silicification, as well as microclinization are recognized. Compared to the alkali-feldspar and albite granites, the microclinization is restricted to the biotite granite, whereas greisenization and albitization increase in the former two granites and reaches their climax in the albite granite. Repeated contrasting acid-and alkaline-based alterations emphasize the fluctuation of the acidic-basic behavior of the fluid as a consequence of dominantly hydrogen-and alkali-exchange reactions.
•Deuteric and hydrothermal alterations of Late Neoproterozoic rare metal-bearing Um Naggat granite.•Textual and mineralogical variations across the UNG pluton.•Implication for paragenesis of various alterations-related minerals.
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GEOZS, IJS, IMTLJ, KILJ, KISLJ, NLZOH, NUK, OILJ, PNG, SAZU, SBCE, SBJE, UILJ, UL, UM, UPCLJ, UPUK, ZAGLJ, ZRSKP
