Vpliv omejevanja rabe antibiotikov v bolnišnicah na odpornost bakterij = The influence of restricted antimicrobial use in hospitals on bacterial resistance
Beović, Bojana
In the past few decades, antibiotic overuse and misuse have been recognized worldwide. Inappropriate usage of antibiotics increases treatment costs and stimulates the spread of resistant bacterial ...strains. Excessive usage of antibiotics in hospitals may be limited by using a list of antibiotics that may be prescribed only by an authorized person, usually an infectious disease specialist. Antibiotic cycling is another method for regulating antibiotic consumption - in this case groups of antibiotics are prescribed in alteration,i. e., one antibiotic regimen is used for a time and then another, and so forth. In some hospitals, guidelines for prescribing antibiotics are implemented through computer-aided decision support systems. Studies of the effects of the above-mentioned methods of antibiotic use restriction have shown reduced treatment costs and, in most cases, improved antimicrobial resistance. Less is known about the effect of their restricted use on the outcome of treatment and duration of hospitalization. In spite of evidence that measures for restricting antibiotic consumption may be effective, the problems related to incorrect usage of antibiotics and bacterial resistance seem to be unresolved. Greater efforts by infectious disease specialists and the general public will be required in the future.
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