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Določanje plazemske koncentracije feritina pri bolnikih s covid-19 = Determination of ferritin plasma concentration in patients with COVID-19 : magistrski študijski program Laboratorijska biomedicinaKok, UrškaDecembra 2019 je bil na Kitajskem v mestu Vuhan odkrit prvi primer novega koronovirusa. Virus se je hitro razširil, kar je povzročilo epidemijo na Kitajskem in v marcu 2020 tudi globalno pandemijo. ... Virus, ki bolezen povzroča, je označen kot SARS-CoV-2. Okužba se prenaša preko kapljic, ki nastajajo v dihalih okuženih ljudi. Večina obolelih ljudi ima blage do zmerne simptome, ki običajno izzvenijo po tednu dni od pojava bolezni. Najpogostejši simptomi so povečana telesna temperatura, utrujenost, motnja vonja ali okusa, prehlad, suh kašelj, slabost, bruhanje, bolečine v mišicah in sklepih. V magistrskem delu smo se osredotočili na koncentracijo feritina, ki je značilni vnetni parameter in je zvišan pri bolnikih s covidom-19. Paciente smo razdelili v tri skupine glede na potek bolezni, in sicer paciente s hujšim potekom bolezni, z blagim potekom in asimptomatske paciente. Vprašanje, ki smo si ga zastavili, je v povezavi s tem, v kolikšnih primerih je koncentracija feritina zvišana v posameznih skupinah pacientov in v kakšni korelaciji so vnetni parametri feritin, CRP in prokalcitonin pri bolnikih s covidom-19. Pri vzorcu moških pacientov nam Dunnov test potrdi statistično pomembne razlike v vrednosti feritina med skupino pacientov brez simptomov in skupino s hujšo obliko covida-19 (p < 0,001 < 0,05), in sicer ima skupina moških pacientov brez simptomov nižjo srednjo vrednost feritina kot skupina moških pacientov s hujšo obliko covida-19. Prav tako zaznamo statistično pomembne razlike med skupino z blažjo obliko in skupino moških pacientov s hujšo obliko covida-19 (p = 0,003 < 0,05). Med skupinama moških pacientov brez simptomov in blažjo obliko ne zaznamo statistično pomembnih razlik v vrednostih feritina (p = 0,398 > 0,05). Pri vzorcu, kjer imamo ženske, potrdimo statistično pomembne razlike med skupino s hujšo obliko covida-19 glede na skupino z asimptomatsko obliko covida-19.Type of material - master's thesis ; adult, seriousPublication and manufacture - Ljubljana : [U. Kok], 2024Language - slovenianCOBISS.SI-ID - 193828355
Author
Kok, Urška
Other authors
Osredkar, Joško, 1955-
Topics
SARS-CoV-2 |
COVID-19 |
Vnetje |
koronavirus |
feritin |
vnetni parametri |
sekvenciranje dolgih odčitkov |
influenca A
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Library | Call number – location, accession no. ... | Copy status |
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Faculty of Pharmacy, Lj. | Knjižnica mlab 616 KOK URŠKA Določanje 365 IN: 0018139 |
available - reading room |
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Kok, Urška | ![]() |
Osredkar, Joško, 1955- | 10691 |
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