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Prevalenca protiteles proti virusu hepatitisa E pri slovenskih bolnikih z velikim tveganjem parenteralno prenosljivih okužb : diplomska naloga = Prevalence of antibodies to hepatitis E virus among Slovenian patients with high risk of parenterally transmitted infections : graduation thesisŠoba, BarbaraVirus hepatitisa E (HEV) se najpogosteje prenaǴa fekalno-oralno in je endemiřen v nekaterih delih Afrike, Azije in Latinske Amerike. OkuÍbe s HEV sov razvitih drÍavah redke in so veřinoma povezane s ... sporadiřnimi vnosi virusaiz endemskih podrořij. V zadnjem řasu se predvsem iz razvitih drÍav vse veř porořa o moÍnem parenteralnem nařinu prenosa HEV. Domneve o moÍnem parenteralnem prenosu HEV temeljijo predvsem na tem, da so v nekaterih raziskavah dokazali statistiřno pomembno viǴjo prevalenco okuÍbe s HEV v skupinah oseb z velikim tveganjem za parenteralno prenosljive okuÍbe v primerjavi s sploǴno populacijo oz. s krvodajalci. V diplomski nalogi smo ugotavljali prevalenco protiteles proti HEV pri slovenskih osebah z velikim tveganjem za parenteralno prenosljive okuÍbe. V raziskavo smo vkljuřili 252 serumskih vzorcev, odvzetih osebam z velikim tveganjem za parenteralno prenosljive okuÍbe, in sicer 39 hemofilikom, 102 hemodializnima bolnikoma ter 111 intravenskim uÍivalcem drog. Prisotnost protiteles smo ugotavljali z encimsko imunskimi testi. Anti-HEV IgG pozitivnih je bilo 7/252 (2,8%) oseb, od tega 2/39 (5,1%) hemofilika, 3/102 (2,9%) hemodializni bolniki in 2/111 (1,8%) intravenska uÍivalca drog. Nihře od sedmih anti-HEV IgG pozitivnih osebni bil anti-HEV IgM pozitiven. Na osnovi rezultatov naǴe raziskave in primerjave le-teh z rezultati podobnih raziskav, ki so bile izvedene drugod posvetu, ter s prevalenco protiteles proti HEV pri slovenskih krvodajalcih, lahko zakljuřimo, da moÍnosti parenteralnega nařina prenosa okuÍbe s HEV pri nekaterih bolnikih z velikim tveganjem za parenteralno prenosljive okuÍbe ne moremo izkljuřiti.Type of material - undergraduate thesis ; adult, seriousPublication and manufacture - Ljubljana : [B. Šoba] ; [BF, Enota medoddelčnega študija mikrobiologije], 2000Language - slovenianCOBISS.SI-ID - 2463864
Author
Šoba, Barbara
Other authors
Poljak, Mario, 1965- |
Seme, Katja, 1966- |
Avšič-Županc, Tatjana
Topics
virusi |
virus hepatitisa E |
HEV |
parenteralen način prenosa |
serološke metode |
protitelesa |
encimsko imunski testi |
ELISA |
EIA |
prevalenca v Sloveniji |
hemofiliki |
hemodializni bolniki |
intravenski uživalci drog |
intravenski uživalci drog |
viruses |
hepatitis E virus |
HEV |
parenteral route of transmission |
serologic methods |
antibodies |
enzyme immunoassays |
ELISA |
EIA |
prevalence in Slovenia |
hemophiliacs |
hemodialysis patients |
intravenous drug users |
intravenous drug users
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Library | Call number – location, accession no. ... | Copy status |
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BF, Dept. of Food Science and Technology, Lj. | Študij mikrobiologije DN 68 a IN: 0012492 |
available - outside loan, loan period: 1 months |
BF, Dept. of Food Science and Technology, Lj. | Študij mikrobiologije DN 68 IN: 0012491 |
available - outside loan, loan period: 1 months |
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DRS, in which the journal is indexed
Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Šoba, Barbara | 22460 |
Poljak, Mario, 1965- | 11622 |
Seme, Katja, 1966- | 14504 |
Avšič-Županc, Tatjana | 10331 |
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