(UL)
-
How perifosine affects liposome-encapsulated drug delivery across a cell barrierTesten, Anže ...The development of efficient drug delivery systems to transport therapeutics across barrier-forming cells remains a challenge. Recently it was shown that liposomes containing perifosine, a synthetic ... analog of lysophosphatidylcholine, efficiently deliver liposome encapsulated content across barrier-forming cells. Methods: To elucidate the mechanism of the delivery, fluorescent and spin labeled analog of perifosine were synthesized and their transport from liposomes to the barrier-forming MDKC cells was measured. Results & Conclusion: Perifosine analogs are rapidly transported from liposomes into cell membranes. The total amount of perifosine accumulated in plasma membranes seems to be the most important factor in efficient transepithelial transport of liposome-encapsulated substances. Lysolipid-containing liposomal formulations seem to be promising candidates as drug delivery systems in general.Source: Therapeutic delivery. - ISSN 2041-5990 (Vol. 6, no. 4, 2015, str. 423-441)Type of material - article, component part ; adult, seriousPublish date - 2015Language - englishCOBISS.SI-ID - 3863665
Author
Testen, Anže |
Podlipec, Rok |
Mravljak, Janez, 1978- |
Orthmann, Andrea |
Šentjurc, Marjeta |
Zeisig, Reiner |
Štrancar, Janez |
Koklič, Tilen
Topics
Liposomi |
dostavni sistemi |
perifosin |
spinsko označeni analogi
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|---|
Testen, Anže | |
Podlipec, Rok | 34747 |
Mravljak, Janez, 1978- | 23419 |
Orthmann, Andrea | |
Šentjurc, Marjeta | 01119 |
Zeisig, Reiner | |
Štrancar, Janez | 18273 |
Koklič, Tilen | 21546 |
Source: Personal bibliographies
and: SICRIS
Select pickup location:
Material pickup by post
Delivery address:
Address is missing from the member's data.
The address retrieval service is currently unavailable, please try again.
By clicking the "OK" button, you will confirm the pickup location selected above and complete the reservation process.
By clicking the "OK" button, you will confirm the above pickup location and delivery address, and complete the reservation process.
By clicking the "OK" button, you will confirm the address selected above and complete the reservation process.
Notification
Automatic login and reservation service currently not available. You can reserve the material on the Biblos portal or try again here later.
Subject headings in COBISS General List of Subject Headings
Select pickup location
The material from the parent unit is free. If the material is delivered to the pickup location from another unit, the library may charge you for this service.
Pickup location | Material status | Reservation |
---|
Reservation in progress
Please wait a moment.
Reservation was successful.
Reservation failed.
Reservation...
Membership card:
Pickup location: