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Physical function and 25-hydroxyvitamin D in dialysis patients - lessons learned from the Slovenian DIAGIB studyPajek, Maja, 1974- ...Aims: Vitamin D stores in dialysis patients may be associated with their muscle function and physical performance. We analyzed associations of 25-hydroxyvitamin D levels with functional test results ... in prevalent hemodialysis patients and healthy controls. Methods: Study sample included 54 dialysis patients and 81 healthy controls who performed a 6-minute walk test, sit-to-stand test, handgrip strength measurement, and self-rated habitual adjusted activity score with Human Activity Profile questionnaire. Adjusted general linear models were used to analyze association of 25-hydroxyvitamin D levels with test results. Results: Serum 25-hydroxyvitamin D concentration was 73.1 % 35.4 nmol/L in dialysis patients and 64.6 % 22 nmol/L in controls (p = 0.12). When adjusted for age, sex, body height, spontaneous gait speed, and dialysis dependence, 25-hydroxyitamin D was significantly positively associated with 6-minute walk test result, explaining 5% of variability in walked distance (B = 0.6 m/nmol/L, p = 0.008) and 12% of variability in adjusted activity score (B = 0.1 point/nmol/L, p < 0.001). There was no significant association with handgrip strength or sit-to-stand performance in adjusted models. Conclusions: Serum 25-hydroxyvitamin D levels are significantly positively associated with submaximal aerobic physical performance and habitual activity level in dialysis patients.Source: Clinical nephrology. - ISSN 0301-0430 (Vol. 88, suppl. 1, 2017, str. S48-S52)Type of material - article, component part ; adult, seriousPublish date - 2017Language - englishCOBISS.SI-ID - 4345201
Author
Pajek, Maja, 1974- |
Čuk, Ivan, 1961- |
Mlinšek, Gregor |
Osredkar, Joško, 1955- |
Pajek, Jernej
Topics
Hemodializa |
vitamin D |
hemodialysis patients |
25-hydroxyvitamin D
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Pajek, Maja, 1974- | 20444 |
Čuk, Ivan, 1961- | 04955 |
Mlinšek, Gregor | 19576 |
Osredkar, Joško, 1955- | 10691 |
Pajek, Jernej | 23258 |
Source: Personal bibliographies
and: SICRIS
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