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  • Cayenne pepper cataplasm "Munari" reduces pain and improves mobility in patients with non-specific chronic low back pain [Elektronski vir]
    Zampieri, Sandra ...
    Objective: To test the cumulative effects of repeated application of Cayenne Pepper Cataplasm "Munari" alone (MUN) or in combination (COMB) with neuromuscular electrical stimulation (NMES) and ... massage on non-specific chronic low back pain (LBP) in terms of safety, pain relief, function and mobility. Design: Before and after intervention trial. Adults suffering from non-specific chronic LBP were treated with "Munari", ten times within 3 weeks. In COMB, following "Munari", 15 minutes of massage and 15 minutes of NMSE were performed. Blood pressure, circulating levels of acute phase proteins (ESR, CRP, CK, albumin), cortisol and inflammatory biomarkers (TNF-a, IL-6, sp-selectin) were assessed before the 1st and after the 10th treatment. At the same time points, measurements included VAS questionnaire, function and mobility tests (ODI, Schober), and serum levels of miRNAs involved in inflammation, pain signalling, and muscle homeostasis. Results: In MUN, blood pressure and pain were significantly reduced. In COMB, function and mobility test's scores significantly improved. In both groups, circulating levels of acute phase response or inflammatory biomarkers didn%t increase, and miRNAs regulating pain signaling were significantly modulated. Conclusions: Repeated Munari applications are safe and effective for the treatment of non-specific chronic LBP, in particular when combined with NMES and massage.
    Type of material - e-article ; adult, serious
    Publish date - 2019
    Language - english
    COBISS.SI-ID - 1541500868