DoCM: a database of curated mutations in cancer

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DoCM: a database of curated mutations in cancer

Ainscough, Benjamin J; Griffith, Malachi; Coffman, Adam C; Wagner, Alex H; Kunisaki, Jason; Choudhary, Mayank Nk; McMichael, Joshua F; Fulton, Robert S; Wilson, Richard K; Griffith, Obi L; Mardis, Elaine R

Nature methods, 10/2016, Volume: 13, Issue: 10

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Large-scale cancer genomics discovery projects such as The Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC) have systematically characterized the molecular lesions in human cancer genomes, thereby laying the foundation for precision cancer medicine. However, a curated set of somatic variants with established relevance to cancer biology is essential for clinical annotation and for use in computational data analysis. We have created a database of curated mutations in cancer.

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