Selais fish (Kryptopterus lais) is a freshwater fish that has high economic value and a high market demand. This species production comes from fishing, and this can cause a decrease in stocks in natural habitats. Artificial feed usage in selais cultivation is still an obstacle and also there is a lack of information in relation to the nutritonal needs of the species. Dedicated feed for selais fish is not yet available on the market, because the information about the feeding habits of the species is limited. The hormonal manipulation techniques are used to improve the quality of production for some freshwater fish. Hormones that are known to have a positive effect on fish growth are thyroxine (T4) and growth hormone. The aim of this research is to study the quality of feed in increasing fish growth by adding thyroxine hormone. The method of this research is experimental with Completely Randomized Design (CRD), 4 treatments and 4 replications. Four dosses of thyroxine hormone are used as control (A), 0,04 mg/kg (B), 0,06 mg/kg (C), and 0,08 mg/kg (D). The organoleptic test showed that the addition of thyroxine hormone with different doses resulted in the same feed quality and physical test showed that the addition of thyroxine hormone to artificial feed with different doses resulted in different feed quality. The results of the proximate analysis showed that the nutritional content of the test feed was within the range of the requirement of selais fish. The addition of the thyroxine hormone with various doses in artificial feed did not significantly affect the growth in weight and length of the selais fish.