Results of Two Cases of Pig-to-Human Kidney Xenotransplantation

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Results of Two Cases of Pig-to-Human Kidney Xenotransplantation

Montgomery, Robert A.; Stern, Jeffrey M.; Lonze, Bonnie E.; Tatapudi, Vasishta S.; Mangiola, Massimo; Wu, Ming; Weldon, Elaina; Lawson, Nikki; Deterville, Cecilia; Dieter, Rebecca A.; Sullivan, Brigitte; Boulton, Gabriella; Parent, Brendan; Piper, Greta; Sommer, Philip; Cawthon, Samantha; Duggan, Erin; Ayares, David; Dandro, Amy; Fazio-Kroll, Ana; Kokkinaki, Maria; Burdorf, Lars; Lorber, Marc; Boeke, Jef D.; Pass, Harvey; Keating, Brendan; Griesemer, Adam; Ali, Nicole M.; Mehta, Sapna A.; Stewart, Zoe A.

New England journal of medicine/The New England journal of medicine, 05/2022, Volume: 386, Issue: 20

Journal Article

Genetically modified pig kidney xenografts were transplanted into two brain-dead human recipients. The xenografts functioned immediately and showed no evidence of acute rejection on serial biopsy over a period of 54 hours. The serum creatinine level decreased in both recipients.

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