20-Year Follow-up of Statins in Children with Familial Hypercholesterolemia

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20-Year Follow-up of Statins in Children with Familial Hypercholesterolemia

Luirink, Ilse K; Wiegman, Albert; Kusters, D. Meeike; Hof, Michel H; Groothoff, Jaap W; de Groot, Eric; Kastelein, John J.P; Hutten, Barbara A

The New England journal of medicine, 10/2019, Volume: 381, Issue: 16

Journal Article

Familial hypercholesterolemia is marked by very elevated low-density lipoprotein cholesterol levels and premature cardiovascular disease. This 20-year follow-up study showed that statin initiation during childhood in affected persons slowed the progression of carotid intima–media thickness and reduced the risk of cardiovascular disease in adulthood.

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