The activization of innovative labor of the employed population is an important prerequisite for socio- economic development in Ukraine. In the context of high IT penetration and intellectualization of Ukraine’s economy, this innovative type of employment will contribute not only to the realization of the population creative and intellectual potential, but also to the improvement of human capital quality. Therefore, the purpose of this article is to develop a methodical approach to determine the degree of activization of the employed population innovative labor. With this aim in mind, a set of methods was used in the research, such as analysis and synthesis, logical generalization and comparison, taxonomic analysis and formalization. The peculiarity of the developed methodical approach is the ability: to evaluate the initial indicators in a certain time period; to group them into partial indicators reflecting the status and features of innovative work of the employed population at the regional level; to analyze the level of partial indicators with the determination of average values in time and regional aspects; to determine the level of the integral indicator. This will allow, on the one hand, making more structured analysis, and on the other, conducting comprehensive analysis of causes of dynamics for both innovative labor and its components.