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  • Primary Prevention of Cardi...
    Estruch, Ramón; Ros, Emilio; Salas-Salvadó, Jordi; Covas, Maria-Isabel; Corella, Dolores; Arós, Fernando; Gómez-Gracia, Enrique; Ruiz-Gutiérrez, Valentina; Fiol, Miquel; Lapetra, José; Lamuela-Raventos, Rosa Maria; Serra-Majem, Lluís; Pintó, Xavier; Basora, Josep; Muñoz, Miguel Angel; Sorlí, José V; Martínez, José Alfredo; Martínez-González, Miguel Angel

    The New England journal of medicine, 04/2013, Volume: 368, Issue: 14
    Journal Article

    In a randomized trial, participants assigned to a Mediterranean diet supplemented with either nuts or extra-virgin olive oil had a significantly lower rate of cardiovascular events at 4.8 years than participants assigned to a low-fat control diet. The traditional Mediterranean diet is characterized by a high intake of olive oil, fruit, nuts, vegetables, and cereals; a moderate intake of fish and poultry; a low intake of dairy products, red meat, processed meats, and sweets; and wine in moderation, consumed with meals. 1 In observational cohort studies 2 , 3 and a secondary prevention trial (the Lyon Diet Heart Study), 4 increasing adherence to the Mediterranean diet has been consistently beneficial with respect to cardiovascular risk. 2 – 4 A systematic review ranked the Mediterranean diet as the most likely dietary model to provide protection against coronary heart disease. 5 Small clinical trials have uncovered . . .