Airway Mucin Concentration as a Marker of Chronic Bronchitis

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Airway Mucin Concentration as a Marker of Chronic Bronchitis

Kesimer, Mehmet; Ford, Amina A; Ceppe, Agathe; Radicioni, Giorgia; Cao, Rui; Davis, C. William; Doerschuk, Claire M; Alexis, Neil E; Anderson, Wayne H; Henderson, Ashley G; Barr, R. Graham; Bleecker, Eugene R; Christenson, Stephanie A; Cooper, Christopher B; Han, MeiLan K; Hansel, Nadia N; Hastie, Annette T; Hoffman, Eric A; Kanner, Richard E; Martinez, Fernando; Paine, Robert; Woodruff, Prescott G; O’Neal, Wanda K; Boucher, Richard C

New England journal of medicine/The New England journal of medicine, 09/2017, Volume: 377, Issue: 10

Journal Article

Chronic bronchitis is currently diagnosed by asking patients if they expectorate sputum on a regular basis. In this study, the concentration of mucin was higher in the induced sputum of patients with chronic bronchitis than in those who did not meet the case definition of the disorder.

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