An electrochemical sensor based on self-made nano-porous pseudo carbon paste electrode (nano-PPCPE) has been successfully developed, and used to detect Cd2+ and Pb2+. The results showed that the electrodes can quantitatively detect trace Cd2+ and Pb2+, and with satisfied limit of detection, which has great significance in electrochemical analysis and detection. Display omitted An electrochemical sensor based on self-made nano-porous pseudo carbon paste electrode (nano-PPCPE) has been successfully developed, and used to detect Cd2+ and Pb2+. The experimental results showed that the electrochemical performance of nanoPPCPE is evidently better than both glassy carbon electrode (GCE) and pure carbon paste electrode (CPE). Then the prepared nano-PPCPE was applied to detect Cd2+ and Pb2+ in standard solution, the results showed that the electrodes can quantitatively detect trace Cd2+ and Pb2+, which has great significance in electrochemical analysis and detection. The linear ranges between the target ions concentration and the DPASV current were from 0.1–3.0 μmol/L, 0.05–4.0 μmol/L for Cd2+ and Pb2+, respectively. And the detection limits were 0.0780 μmol/L and 0.0292 μmol/L, respectively. Moreover, the preparation of the nano-PPCPE is cheap, simple and has important practical value.