Recent studies have increasingly investigated construction methods for tunnel excavation because of growing underground space development. Although the New Austrian tunneling method (NATM)—a representative tunnel excavation method—can be applied to various ground conditions, as well as having good constructability and economic feasibility, it suffers from problems such as vibration and noise. By contrast, excavation using a tunnel boring machine (TBM)—a representative mechanized construction method—affords advantages such as stable excavation, minimized ground and environmental damage, noise, and vibration. However, it cannot be applied easily to various ground conditions, and it suffers from problems such as high construction costs and delays owing to equipment defects. Therefore, the simultaneous pilot tunnel excavation using the TBM—which affords advantages such as constructability, economic feasibility, and minimized noise and vibration—and rear enlargement blasting using NATM was investigated in this study. A protection shield was installed to minimize accidents occurring from equipment defects (a disadvantage of TBM) and analyze the decrease in the effect of NATM blasting, which depends on the use of the protection shield and the separation distance through 3D numerical analysis.