E-resources
Peer reviewed
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Fan, Lian-Feng; Wang, Pu-Sheng; Gong, Liu-Zhu
Organic letters, 09/2019, Volume: 21, Issue: 17Journal Article
Monodentate phosphorus ligands have been found to enable the palladium-catalyzed allylic C–H alkylation reaction of terminal alkenes with a wide variety of carbon nucleophiles. Moreover, an asymmetric allylic C–H alkylation of terminal alkenes with pyrazol-5-ones has been established in the presence of chiral phosphoramidite ligand and chiral phosphoric acid as co-catalyst. Mechanistic studies suggest that a ternary Pd(0) complex, coordinated with a monodentate phosphorus ligand, benzoquinone, and alkene, is most likely to be an active species.
