Here, we review the neural correlates of cognitive control associated with bilingualism. We demonstrate that lifelong practice managing two languages orchestrates global changes to both the structure and function of the brain. Compared with monolinguals, bilinguals generally show greater gray matter volume, especially in perceptual/motor regions, greater white matter integrity, and greater functional connectivity between gray matter regions. These changes complement electroencephalography findings showing that bilinguals devote neural resources earlier than monolinguals. Parallel functional findings emerge from the functional magnetic resonance imaging literature: bilinguals show reduced frontal activity, suggesting that they do not need to rely on top‐down mechanisms to the same extent as monolinguals. This shift for bilinguals to rely more on subcortical/posterior regions, which we term the bilingual anterior‐to‐posterior and subcortical shift (BAPSS), fits with results from cognitive aging studies and helps to explain why bilinguals experience cognitive decline at later stages of development than monolinguals.