Burn injuries are not uncommon, and a decade ago, more than one subject with major burn injury arrived in our emergency department each day. We here report of some basic epidemiological data of burn injury for a period of 11 years and propose an approach for prevention and care of burn. Authors obtained the records of the 5500 patients admitted in tertiary care unit of central India from March 2005 to March 2016. The preclinical, clinical, and stage of resolution variables are included in the customized proforma. Few additional data was available in the case sheets of year 2016 and analyzed separately. Data are analyzed using Statistical Package for the Social Sciences. The mean age was 28.6 years with standard deviation of 13.26. Male to female ratio was 1:1.36. Frequency from neighboring district (51.81%), Hindus (86.83%), accidental intent of burn (85.2%), flame type of injuries (76.45%), kerosene as agent of burn (69.4%), home as place of burn (90.92%) are other recognizable variables. Clinical and outcome variables are total body surface area (> 50%) in 57%, hospital stay (> 3 days) in 61.5%, mortality rate (46%), left against medical advice (LAMA) in 36.4%, and survival rate (15.4%). In a select group of 500 patients, some other useful variables like careless attitude in handling kerosene (84%), illiteracy (74.2%), low socioeconomic status (83.4%), married status (75.8%), and family size (> 3) in 74.8% were recorded. In India, burns are preventable by elimination of kerosene/distribution in closed containers. Community-based prevention program is a must. Author’s “SIREN” reaction plan is for first responders. Authors prepared a burn management guideline for primary healthcare level with an acronym “ALERT-DAY” protocol to decrease morbidity of burn. Upgradation of existing burn center is essential to curb the mortality and LAMA rates and improve the survival.