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Weber, Bernardete; Galante, Andrea P; de Sousa Lara, Enilda; Moriguchi, Emilio H; Bruscato, Neide M; Kesties, Josiele; Backes, Luciano M; Reolão, Bruna R; Reolão, Jose B.C; Deucher, Keyla L.A.L; Cantarelli, Maiara; Rampazzo, Daniela; Cardos, Andrea F.R; Negrão, Mayara G; Alencar, Mônica F.A; Pinho, Priscila M; Carvalho, Ana P.P.F; Heyde, Raul V; Nagano, Francisca E.Z; Resende, Fernanda P; Tabalipa, Ranata; Araujo, Hevila; Teixeira, Maria L.V; Zuchinali, Priccila; Fracasso, Bianca M; Hilário, Thamires; Carlos, Daniele M.O; Carvalho, Daniele A; Gonçalves, Marília S; Vasconcelos, Valdiana B; Romano, Marcelo L.P; Jardim, César A; Schmitt, Alessandra R; Silva, Flávia M; Fink, Jaqueline S; Prates, Clarice F; Vieira, Cristiane S; Adorne, Elaine F; Teixeira, Joise M; Pellegrini, Lívia A; Pinto, Jéssika C; Costa, Ariane A; Lucas, Marilia C.S; Damiani, Monica; Ramos, Salvador S; Cabral, Ana M.P; Medeiros, Auriene L; Leda, Neuma M.F.S; Souza, Camila V.S; Souza, Larissa C.F; Santos, Letícia S; Hoffmann, Meg S; Vasconcelos, Daniel F; Santos, Alexsandro F; Sousa, Rosângela M.L; Lima, Maria T.M.A; Teixeira, Adriana F; Modanesi, Paulo V.G; Rocha, Bárbara R.S; Teti, Cristina; Palácio, Bruna M; Uehara, Rose M; Sasso, Sandramara; Cadinha, Ana C.A.H; Magnoni, Daniel; Monteiro, Aline S; Santos, Karina G. dos; Moreira, Priscila; Russo, Diana S; Silveira, Izabele V; Boklis, Mirena; Dias, Glauber M; Cavalcanti, Adrilene C; Rodrigues, Isa G; Leal, Tallita V; Sahade, Viviane; Amaral, Daniele A; Barretto, Marília M.S; Reis, Nailson A; Fontes, Jessica M.S; Ferreira, Raphaela C; Ferreira, Lauren S; Azevedo, Norlai A; Martins, Celma M; Kato, Juliana T; Machado, Valéria A; Lima, Hatanne C.F.M; Saldanha, Tânia M; Feres, Naoel H; Reis, Silvia R.L; Penafort, Andreza M; Farias, Geysa M.N; de los Santos, Mônica L.P; Ambrozio, Cíntia L; Boemo, Jorge L; Lima, Súsi M.B; Barretta, Claiza; Specht, Clarice M; de Souza, Simone R; Rodrigues, Priscila A
The American heart journal, 01/2016, Volume: 171, Issue: 1Journal Article
Abstract This article reports the rationale for the Brazilian Cardioprotective Nutritional Program (BALANCE Program) Trial. This pragmatic, multicenter, nationwide, randomized, concealed, controlled trial was designed to investigate the effects of the BALANCE Program in reducing cardiovascular events. The BALANCE Program consists of a prescribed diet guided by nutritional content recommendations from Brazilian national guidelines using a unique nutritional education strategy, which includes suggestions of affordable foods. In addition, the Program focuses on intensive follow-up through one-on-one visits, group sessions, and phone calls. In this trial, participants 45 years or older with any evidence of established cardiovascular disease will be randomized to the BALANCE or control groups. Those in the BALANCE group will receive the afore mentioned program interventions, while controls will be given generic advice on how to follow a low-fat, low-energy, low-sodium, and low-cholesterol diet, with a view to achieving Brazilian nutritional guideline recommendations. The primary outcome is a composite of death (any cause), cardiac arrest, acute myocardial infarction, stroke, myocardial revascularization, amputation for peripheral arterial disease, or hospitalization for unstable angina. A total of 2468 patients will be enrolled in 34 sites and followed up for up to 48 months. If the BALANCE Program is found to decrease cardiovascular events and reduce risk factors, this may represent an advance in the care of patients with cardiovascular disease.
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