This study aims to improve students' motivation and learning outcomes by applying Edmodo-based e-learning model in the Biology Education Study Program of Medan State University. The research method used is class action research with the application of two cycles. The subjects of this study were 17 students who took basic accounting courses and research objects of activities that took place during the learning process. Data analysis techniques used are descriptive quantitative with percentages used to measure the level of motivation of students, for the results of learning is evaluated at the end of each learning. The results of class action research obtained by the application of Edmodo can improve students' motivation and learning outcomes. This is evident from the implementation of actions starting from pre-action, cycle I, and cycle II. Student learning motivation is said to succeed with an average of 75-100%. The results obtained in cycle action I were 84.11% and 88.11% in cycle II. While the percentage of student learning outcomes also increased. The increase in pre-action from 50.75 to 73.53 in cycle I increased by 22.77, from 73.53 to 87.35 in cycle II which means an increase of 13.82.