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冯雪; 王海伟; 李闻思; 杨新同; 孙存; 赵媛; 赵朋波; 张建强
山东大学耳鼻喉眼学报, 2020, Volume: 34, Issue: 4Journal Article
R774.1; 目的 应用频域光学相干断层成像(SD-OCT)测量视网膜血管管径,分析高血压类型与视网膜血管管径的关系.方法研究为横断面研究,将103例高血压患者共103眼纳入研究.根据高血压类型将入组患者分为3个组:单纯收缩期高血压(ISH)组34例(34眼)、单纯舒张期高血压(IDH)组34例(34眼)、收缩期和舒张期联合性高血压(SDH)组35例(35眼),应用SD-OCT测量视网膜血管管径,分析3组之间的视网膜动脉直径(CRAE)、视网膜静脉直径(CRVE)、视网膜动静脉直径比例(AVR)的差异.应用logistic回归分析血压与AVR的关系.结果3组之间在CRAE、AVR方面相比,差异均有统计学意义(F=4.543、4.308,P=0.013、0.016),SDH组CRAE、AVR最小,IDH组CRAE、AVR最大.3组之间在CRVE方面相比,差异无统计学意义(F=0.417,P=0.660).多因素logistic回归分析,控制年龄、性别等混杂因素后,高收缩压与AVR<0.7的发生显著相关(OR=1.080,P=0.015).结论三种类型高血压中,SDH型高血压患者的视网膜动脉最细、视网膜动静脉直径比例最小.高收缩压是AVR<0.7发生的危险因素.
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