The paper describes the energy consumption and GHG production comparison of three transport modes – road, rail and waterborne. The calculations are done according to the legislation in force – standard EN 16 258:2012 Methodology for calculation and declaration of energy consumption and GHG emissions of transport services (freight and passengers). The results have high informative value because they take into account energy consumption and emissions from primary and secondary consideration. The calculation is done by real fuel consumption values (road and waterborne) and by simulation of energy consumption (railway). The energy and emission coefficients from the standard EN were used for estimating the results according to the well-to-wheels and tank-to-wheels principles.