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Wang, Jian; Li, Hao; Zu, Liansuo; Jiang, Wei; Xie, Hexin; Duan, Wenhu; Wang, Wei
Journal of the American Chemical Society, 10/2006, Volume: 128, Issue: 39Journal Article
Conjugate addition reactions of a wide range of nucleophilic enol species with enones, catalyzed by a cinchona alkaloid derived thiourea organocatalyst, have been developed with attending good yields and high enantioselectivities under a mild reaction condition. The general method provides an efficient approach to the preparation of versatile building blocks possessing various functional groups.
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