Direct Synthesis of Arylketones by Nickel-Catalyzed Addition of Arylboronic Acids to Nitriles

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Direct Synthesis of Arylketones by Nickel-Catalyzed Addition of Arylboronic Acids to Nitriles

Wong, Ying-Chieh; Parthasarathy, Kanniyappan; Cheng, Chien-Hong

Organic letters, 04/2010, Volume: 12, Issue: 8

Journal Article

A convenient and efficient method for the synthesis of various arylketones by nickel-catalyzed addition of arylboronic acids to nitriles is described. A catalytic cycle involving Ni(II) species as the catalytic intermediates is proposed to account for the present catalytic reaction.

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Wong, Ying-Chieh | Parthasarathy, Kanniyappan | Cheng, Chien-Hong

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