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Peer reviewed
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Zu, Liansuo; Xie, Hexin; Li, Hao; Wang, Jian; Wang, Wei
Organic letters, 03/2008, Volume: 10, Issue: 6Journal Article
Fluorous (S) pyrrolidine sulfonamide serves as an efficient promoter for highly enantioselective aldol reactions of ketones and aldehydes with aromatic aldehydes on water. A notable feature of the organocatalyst is that it can be recovered from the reaction mixtures by simple fluorous solid-phase extraction and subsequently reused (up to seven cycles) without a significant loss of catalytic activity and stereoselectivity.
