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Kiem, Phan Van; Tri, Mai Dinh; Tuong, Le Vo Dinh; Tung, Nguyen Huu; Hanh, Nguyen Ngoc; Quang, Tran Hong; Cuong, Nguyen Xuan; Minh, Chau Van; Choi, Eun-Mi; Kim, Young Ho
Chemical & pharmaceutical bulletin, 09/2008, Volume: 56, Issue: 9Journal Article
Two new phenyl glycosides, mangliesides A and B (1, 2), a new ionol glycoside, manglieside C (3), two new lignan glycosides, mangliesides D and E (4, 5), were isolated from the leaves of Manglietia phuthoensis, along with two known lignans, 3-methoxymagnolol (6) and obovatol (7). Their structures were established by means of 1D and 2D NMR, electrospray ionization (ESI)-MS and HR-ESI-MS experiments. Among them, compounds 2 and 5 significantly (p<0.05) increased the growth and differentiation of osteoblastic MC3T3-E1 cells in vitro.
