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Borghi, Elisa; Pagani, Elisabetta; Mancuso, Roberta; Delbue, Serena; Valli, Marilena; Mazziotti, Romina; Giordano, Lucio; Micheli, Roberto; Ferrante, Pasquale
Journal of medical virology, March 2005, Volume: 75, Issue: 3Journal Article
This is a case study of a child who developed roseola infantum first, then varicella, and was later affected by acute cerebellar syndrome, severe truncal ataxia, and myoclonic dystonia. Human herpesvirus 6 (HHV‐6) A and B were detected in the cerebrospinal fluid (CSF) and peripheral blood, respectively, upon ataxia onset. The intricacy of this case suggests multifaceted conclusions ranging from the need for a multidirectional approach to neurological diseases, to confirmation of a more pronounced neurotropism of HHV‐6A and a possible role of viruses in myoclonic dystonia syndrome, although this last hypothesis should be confirmed by larger studies. J. Med. Virol. 75:427–429, 2005. © 2005 Wiley‐Liss, Inc.
