The present study evaluated sustainable development indicators of the Nekarood Watershed in Iran using global Sustainable Development Goals (SDGs) indicators. Identifying values and thresholds, justification of optimum values, ranking, and performance assessment of the associated SDGs' indicators were accordingly addressed. Moreover, due to a lack of complete information and ecological conditions, 77 indicators were selected based on compliance with the indicators of global SDGs. These indicators were used to evaluate the development situation of the study area. The indicators were then normalized, weighed, aggregated, and ranked into four categories from achieving to highly challenging. The results showed that among the SDGs, five goals performed above the mean of the global sustainable development goals. So, goals 3 and 1 had the highest performance of 69.82 and 57.97 %, respectively. Likewise, goals 7 and 16 showed the lowest performance beyond the global average of 51.08 and 54.62 %, respectively. SDG3-1-1, SDG3-1-2, SDG3-2-1, and SDG3-2-2 indicators with 100 % performance positively affected SDG3. SDG1-5-1 indicator with 100 % performance also had the most positive effect on SDG1. The performances of nine goals were also lower than the global mean. In this case, the lowest performance was assigned to goal 2, followed by goals 9, 17, 10, and 6, respectively, with 15.24, 19.71, 22.19, 24.98, and 45.78 %. SDG2-4-2, SDG2-4-1, and SDG2-3-1 indicators had the most negative effect on the performance of SDG2. SDG9-2-2 and SDG10-4-1 indicators also had the most negative effect on goals 9 and 10, respectively. The highest performance of the indicators was associated with the Ministry of Health and Medical Education, and the lowest was related to the Ministries of Agriculture Jihad and the Ministry of Industry, Mine, and Trade. The results of the present study verified an overall performance of 36.42 % for the Nekarood Watershed concerning the global SDGs, representing significantly challenging conditions. Display omitted •Sustainable development goals (SDGs) were examined in the Nekarood Watershed, Iran.•Five United Nation's SDGs outperformed the global mean in the study watershed.•Zero hunger (2nd) and healthy life (3rd) SDGs had the best and worst performance.•The Ministry of Health and Medical Education performed excellent to achieve SDGs.•The whole performance of the watershed was 37.51 %, notifying substantial challenges.