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Nagasawa, Y; Matsusaki, Y; Nobuta, T; Tada, N; Miura, T; Itoh, A
2015-July-27, Volume: 5, Issue: 78Journal Article
This study reports a safe, mild, and environmentally benign synthetic method toward 2-aryl-4-quinazolinones from aromatic aldehydes and aminobenzamides through a cyclization-oxidation sequence using a catalytic amount of iodine, which serves as both a Lewis acid and an oxidant, harmless visible light irradiation, and molecular oxygen as the terminal oxidant. This study reports a safe, mild, and environmentally benign synthetic method toward 2-aryl-4-quinazolinones through a cyclization-oxidation sequence using a catalytic amount of iodine, harmless visible light irradiation, and molecular oxygen.
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