Efficient sweat release and heat dissipation are required for functional textiles that improve comfort and productivity while being worn in daily life. However, the porous structure of textiles exhibits an opposite effect on water transport and heat transfer capacities, leading to a longstanding bottleneck for the design of multifunctional drying and cooling textiles. Here, a biomimetic transpiration textile based on the hierarchical and interconnected network of vascular plants is demonstrated for highly efficient personal drying and cooling. The transpiration‐inspired design offers a textile with distinct advantages, including a desired one‐way water transport index (1072%), rapid water evaporation rate (0.36 g h−1), and outstanding through‐plane (0.182 W m−1 K−1) and in‐plane (1.137 W m−1 K−1) thermal conductivities. Moreover, based on the optimized performance, plausible mechanisms are proposed and calculated to provide insight into the water transport and heat transfer within the hierarchical and interconnected network, which provide promising benefits to the development of multifunctional drying and cooling textiles. Overall, the successful synthesis of this biomimetic transpiration textile provides a comfortable microclimate to the human body, thus satisfying the growing demand for better health, productivity, and sustainability. A biomimetic transpiration textile with a hierarchically fibrous structure and an interconnected boron nitride nanosheet network is fabricated for personal drying and cooling. Benefitting from its optimized structure, this textile exhibits a desired directional water transport capacity and unimpeded heat dissipation, which synergistically contribute to the highly efficient drying and cooling, thus creating a comfortable microclimate for the human body.