Baseline Characteristic KIF6 Tested N = 647 Matched Control N - 647 p value Age (years; mean±SD) 60 ± 12 59 ± 11 NS Males (%) 45.6 44.4 NS Mail Prescription Channel (%) 54.3 51 NS # of Chronic Medications (mean±SD) 5 ± 4 5 ± 4 NS Statin Out of Pocket Cost ($, mean±SD) 30 ± 37 34 ± 41 NS Total Out of Packet Cost ($, mean±SD) 244 ± 290 236 ± 287 NS Deyo-Charlson score (mean±SD) 0.61 ± 1.12 0.70 ± 1.20 NS Married (%) 78.8 78.8 NS High School Education (%) 41 44.2 NS Income < $30,000 (%) 12.7 13.9 NS Smoking (%) 15.6 14.5 NS Acute Coronary Syndrome (%) 11.6 10.8 NS Stable CHD (%) 10.2 9.3 NS Stroke (%) 0.8 1.5 NS Transient Ischemic Attack (%) 1.7 1.7 NS Peripheral Arterial Disease (%) 2.5 3.4 NS Diabetes (%) 22.7 29.2 <0.05 Hypertension (%) 57.2 64 <0.05 Cancer (%) 7.7 6.8 NS Chronic Kidney Disease (%) 3.2 2.9 NS Depression (%) 5.4 4.6 NS Alzheimer's Disease (%) 0.2 0.6 NS Follow-up Health Care Provider Contacts Office visits (mean±SD) 5 ± 6 5 ± 5 NS Adjusted Outcomes in KIF6-Tested Group vs Matched Controls 6-month Adherence (PDC >=0.80) OR 1.99 (1.57-2.51), p<0.0001 6-month Persistence OR 1.83 (1.44-2.32), p<0.0001 Table Categorical & continuous variables analyzed using chi-squared or Fishers exact test, & t-tests, respectively (significance at p<0.05).