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Huang, Hao; Kuang, Hongying; Thomas, Tracey R.; Wei, Daimin; Zhang, Heping
Fertility and sterility, June 2024, 2024-Jun, 2024-06-00, 20240601, Volume: 121, Issue: 6Journal Article
Randomized controlled trials and intent-to-treat analyses are important for infertility clinical studies. Dropouts or crossovers during the study process will disrupt the randomization design and affect the intent-to-treat analysis. In this review, we have briefly introduced the occurrence of dropout and crossover from our previous Reproductive Medicine Network and other related studies and provided some experience obtained from these studies on how to minimize and reduce the occurrence of dropout and crossover for infertility randomized clinical studies.
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