Around 80% of the food consumed worldwide is provided by agriculture, and almost 30% of these products are affected by phytopathogenic agents, which cause numerous plant diseases.Microorganisms have been used as biocontrol agents to eliminate or decrease damage caused by phytopathogens.For the application of biocontrol agents, such as strains of Bacillus velezensis, several parameters need to be considered, including their habitat and molecular and biochemical conditions, such as plant growth promotion and antifungal activity.B. velezensis strains also have potential as control agents against nematodes in greenhouse cultivation, as probiotic supplements for feed, to pretreat lignocellulosic materials, or in wastewater treatments through the enzymes they produce. Many microorganisms have been reported as bioagents for producing ecofriendly, cost-effective, and safe products. Some Bacillus species of bacteria can be used in agricultural applications. Bacillus velezensis in particular has shown promising results for controlling destructive phytopathogens and in biofungicide manufacturing. Some B. velezensis strains can promote plant growth and display antibiotic activities against plant pathogen agents. In this review, we focus on the often-overlooked potential properties of B. velezensis as a bioagent for applications that will extend beyond the traditional agricultural uses. We delve into its versatility and future prospects, the challenges such uses may encounter, and some drawbacks associated with B. velezensis-based products. Many microorganisms have been reported as bioagents for producing ecofriendly, cost-effective, and safe products. Some Bacillus species of bacteria can be used in agricultural applications. Bacillus velezensis in particular has shown promising results for controlling destructive phytopathogens and in biofungicide manufacturing. Some B. velezensis strains can promote plant growth and display antibiotic activities against plant pathogen agents. In this review, we focus on the often-overlooked potential properties of B. velezensis as a bioagent for applications that will extend beyond the traditional agricultural uses. We delve into its versatility and future prospects, the challenges such uses may encounter, and some drawbacks associated with B. velezensis-based products.