Abstract This study evaluated the effects of psychosocial factors on the risk of WRMD symptoms in Brazilian footwear industry workers. The workers’ perceptions regarding psychosocial factors and frequency of body pain were collected through a self-administered questionnaire. Logistic regression modeling was used to estimate the risk (Odds Ratio) of a worker more frequently exhibiting a symptom due to psychosocial factors. It was observed that some psychosocial factors, such as stress, contribute to WRMD in men, increasing the chance of symptoms in the knee (OR=3.07; p-value=0.036). In women, the ‘job dissatisfaction’ factor contributes to WRMD, increasing the chance of pain in the elbow (OR=4.83; p-value=0.007). It was concluded that a greater number of psychosocial factors influences the development of WRMD in male workers, although the effect these factors be discreet. In women, less psychosocial factors are related to WRMD, however its influence is very significant.