E-resources
Peer reviewed
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Tong, Min-Chao; Chen, Xuan; Li, Jun; Huang, Rong; Tao, Haiyan; Wang, Chun-Jiang
Angewandte Chemie (International ed.), April 25, 2014, Volume: 53, Issue: 18Journal Article
An unprecedented catalytic asymmetric inverse‐electron‐demand aza‐Diels–Alder reaction of indoles with in situ formed azoalkenes is reported. A diverse set of 2,3‐fused indoline heterocycles were achieved in generally good yields (up to 97 %) with high regioselectivity and diastereoselectivity (>20:1 d.r.), and with excellent enantioselectivity (up to 99 % ee). In(verse) demand: The unprecedented catalytic asymmetric inverse‐electron‐demand aza‐Diels–Alder reaction of indoles with in situ formed azoalkenes is reported. A diverse set of 2,3‐fused indoline heterocycles were produced in generally good yields with high regioselectivity and diastereoselectivity, and with excellent enantioselectivity.
