Non-conventional machining process for instance, wire electrical discharge machining (WEDM) of titanium alloys is gaining attention due to non-contact nature of this process. To deepen the understanding in this area, this study investigates surface generation, kerf width, discharge gap, material removal rate and wire degradation during WEDM of Ti6Al4V alloy. Pulse on time (4–10 μs), flushing pressure (7–18 MPa) and wire tension (800–1700 gf) were varied and resulting influences on output parameters were analysed. It was found that, machined surfaces consist of multi-layered recast layer with the presence of cracks, holes as well as traces of materials from electrode wire. The composition and roughness of the machined surface varies slightly with respect to machining condition without following any trend. In addition, deformation and morphology of deformed wire electrode after the WEDM process was also reported in this study.