E-resources
Peer reviewed
Open access
-
Salsano, Antonio; Di Mauro, Michele; Labate, Laura; Della Corte, Alessandro; Lo Presti, Federica; De Bonis, Michele; Trumello, Cinzia; Rinaldi, Mauro; Cura Stura, Erik; Actis Dato, Guglielmo; Punta, Giuseppe; Nicolini, Francesco; Carino, Davide; De Vincentiis, Carlo; Garatti, Andrea; Cappabianca, Giangiuseppe; Musazzi, Andrea; Cugola, Diego; Merlo, Maurizio; Pacini, Davide; Folesani, Gianluca; Sponga, Sandro; Vendramin, Igor; Pilozzi Casado, Alberto; Rosato, Francesco; Mikus, Elisa; Savini, Carlo; Onorati, Francesco; Luciani, Giovanni Battista; Scrofani, Roberto; Epifani, Francesco; Musumeci, Francesco; Lio, Antonio; Colli, Andrea; Falcetta, Giosuè; Nicolardi, Salvatore; Zaccaria, Salvatore; Vizzardi, Enrico; Pantaleo, Antonio; Minniti, Giuseppe; Villa, Emmanuel; Dalla Tomba, Margherita; Pollari, Francesco; Barili, Fabio; Parolari, Alessandro; Lorusso, Roberto; Santini, Francesco
Journal of clinical medicine, 12/2023, Volume: 13, Issue: 1Journal Article
Infective endocarditis (IE) is a serious disease, and in many cases, surgery is necessary. Whether the type of prosthesis implanted for aortic valve replacement (AVR) for IE impacts patient survival is a matter of debate. The aim of the present study is to quantify differences in long-term survival and recurrence of endocarditis AVR for IE according to prosthesis type among patients aged 40 to 65 years. This was an analysis of the INFECT-REGISTRY. Trends in proportion to the use of mechanical prostheses versus biological ones over time were tested by applying the sieve bootstrapped t-test. Confounders were adjusted using the optimal full-matching propensity score. The difference in overall survival was compared using the Cox model, whereas the differences in recurrence of endocarditis were evaluated using the Gray test. Overall, 4365 patients were diagnosed and operated on for IE from 2000 to 2021. Of these, 549, aged between 40 and 65 years, underwent AVR. A total of 268 (48.8%) received mechanical prostheses, and 281 (51.2%) received biological ones. A significant trend in the reduction of implantation of mechanical vs. biological prostheses was observed during the study period ( < 0.0001). Long-term survival was significantly higher among patients receiving a mechanical prosthesis than those receiving a biological prosthesis (hazard ratio HR 0.546, 95% CI: 0.322-0.926, = 0.025). Mechanical prostheses were associated with significantly less recurrent endocarditis after AVR than biological prostheses (HR 0.268, 95%CI: 0.077-0.933, = 0.039). The present analysis of the INFECT-REGISTRY shows increased survival and reduced recurrence of endocarditis after a mechanical aortic valve prosthesis implant for IE in middle-aged patients.
Author
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|
Source: Personal bibliographies
and: SICRIS
The material is available in full text. If you wish to order the material anyway, click the Continue button.