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Castro, Eumenia, MD, PhD; Santiago, Nahir Cortes, MD, PhD; Ferguson, Lizmery M. Suarez, MS; Rao, Pulivarthi H., PhD; Venkatramani, Rajkumar, MD,MS,FAAP; López-Terrada, Dolores, MD, PhD
Human pathology, 07/2016, Volume: 53Journal Article
Summary We hereby report an unusual gastric tumor arising from the pyloric wall of the stomach in a 9-year old child harboring the exceptionally rare translocation t(7;12) resulting in ACTB-GLI1 gene fusion. This tumor has been previously classified as pericytoma with t(7;12) and described in 6 patients, two of them children. We discuss the challenges in recognizing this rare entity and the importance of the molecular studies in establishing the correct diagnosis. Our case is the first report of this type arising in the stomach of a child.
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